Factors associated with mortality in mechanically ventilated patients with severe acute respiratory syndrome due to COVID-19 evolution

Oliveira, João Paulo Arruda de; Costa, Adriana; Lopes, Agnaldo José; Ferreira, Arthur de Sá; Reis, Luis Felipe Fonseca

doi:10.5935/2965-2774.20230203-en

Crit Care Sci

2023

DOI: 10.5935/2965-2774.20230203-en

|View full text |Cite

Factors associated with mortality in mechanically ventilated patients with severe acute respiratory syndrome due to COVID-19 evolution

João Paulo Arruda de Oliveira¹,

Adriana Costa²,

Agnaldo José Lopes³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Evolução Clínica e Fatores Prognósticos de Pacientes Oncológicos com Covid-19 em Ventilação Mecânica

Santos,

Cavalcante,

Almeida

et al. 2024

Rev. Bras. Cancerol.

View full text Add to dashboard Cite

Introdução: Pacientes com câncer apresentaram risco de desenvolver quadros respiratórios graves quando acometidos por covid-19, com necessidade de suporte intensivo e de ventilação mecânica invasiva (VMI). Objetivo: Avaliar os fatores associados ao óbito em pacientes oncológicos que tiveram covid-19 e evoluíram com insuficiência respiratória e necessidade de VMI. Método: Estudo de coorte retrospectivo de pacientes com câncer em uma unidade de terapia intensiva (UTI) oncológica, com covid-19 e em VMI de abril de 2020 a dezembro de 2021. Foram incluídos de forma sequencial todos os pacientes com câncer admitidos na UTI em VMI ou que evoluíram com VMI por agravamento da covid-19, sendo excluídos aqueles em controle da doença oncológica há mais de cinco anos. Para a análise estatística, foram utilizadas medidas de tendência central e dispersão, assim como frequências absolutas e relativas. A regressão logística múltipla foi aplicada para a avaliação dos fatores associados à mortalidade, considerando estatisticamente significantes valores de p < 0,05. Resultados: Foram incluídos no estudo 85 pacientes. O óbito foi maior entre os pacientes com tumores sólidos (OR = 3,64; IC 95%: 1,06-12,52; p = 0,04), entre os que necessitaram de suporte renal durante a internação na UTI (OR = 6,88; IC 95%: 1,82-25,98; p = 0,004), os que não puderam ser extubados (OR = 8,00; IC 95%: 2,16-29,67; p = 0,002) e os que apresentaram o valor de pressão de distensão alveolar maior do que 15cmH2O por pelo menos um dia (OR = 5,9; IC 95%: 1,76-19,80; p = 0,004). Conclusão: Características clínicas e de VMI estavam associadas à morte de pacientes oncológicos com covid-19 e em VMI.

show abstract

Evolução Clínica e Fatores Prognósticos de Pacientes Oncológicos com Covid-19 em Ventilação Mecânica

Santos,

Cavalcante,

Almeida

et al. 2024

Rev. Bras. Cancerol.

View full text Add to dashboard Cite

show abstract

Survival and risk of death in Covid-19 patients admitted to a public hospital in the Legal Amazon

De Andrade,

Mariano,

Pereira

et al. 2024

Cad. Pedagógico

View full text Add to dashboard Cite

Objective: To evaluate survival and risk of mortality in COVID-19 patients admitted to a public hospital located in the Legal Amazon. Method: A retrospective longitudinal documentary study, in which 196 medical records of patients admitted from April to August 2020, at the General Hospital of Palmas, diagnosed with COVID-19, were assessed. Socioeconomic data, age, sex, comorbidities, and disease outcome were collected from the records. Results: The average age was 58.6±16 years. Male sex was predominant (66.8%) and individuals with comorbidities (77%). It was observed that 76.14% of the patients were between 40 and 80 years of age. The Kaplan-Meier curve demonstrated a decline in survival over time, indicating that the likelihood of a patient surviving for 16 days is around 50%. The Log-rank test showed a statistical difference for the variables age (p = 0.01) and cancer (p = 0.02), suggesting a reduction in the probability of survival in older patients with cancer. The Cox regression identified that the risk of death in patients between 60 and 79 years was approximately 3 times higher than in those aged 40, while in those aged 80 or older, it was 6 times higher. In the same model, the risk of death in patients with obesity was 98% higher, and 2.11 times higher in patients with cancer. Conclusions: The research provided important insights into the behavior of COVID-19 in the Legal Amazon, which will support the response to the virus and other health crises.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

334 Leonard St

Brooklyn, NY 11211

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Factors associated with mortality in mechanically ventilated patients with severe acute respiratory syndrome due to COVID-19 evolution

Cited by 2 publications

References 0 publications

Evolução Clínica e Fatores Prognósticos de Pacientes Oncológicos com Covid-19 em Ventilação Mecânica

Evolução Clínica e Fatores Prognósticos de Pacientes Oncológicos com Covid-19 em Ventilação Mecânica

Survival and risk of death in Covid-19 patients admitted to a public hospital in the Legal Amazon

Contact Info

Product

Resources

About