Effects of atelectatic areas on the surrounding lung tissue during mechanical ventilation in an experimental model of acute lung injury induced by lipopolysaccharide
Lídia Maria Carneiro Fonseca,
Maycon Moura Reboredo,
Leda Marília Fonseca Lucinda
et al.
Abstract:Objective
To assess the effect of atelectasis during mechanical ventilation on the
periatelectatic and normal lung regions in a model of atelectasis in rats
with acute lung injury induced by lipopolysaccharide.
Methods
Twenty-four rats were randomized into the following four groups, each with 6
animals: the Saline-Control Group, Lipopolysaccharide Control Group,
Saline-Atelectasis Group, and Lipopolysaccharide Atelectasis Group. Acute
lung injury was induced by intraper… Show more
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