Evolutive Study of Rheumatic Carditis Cases Treated with Corticosteroids in a
            Public Hospital

Lemos, Fernanda Maria Correia Ferreira; Herdy, Gesmar Volga Haddad; Valete, Cristina Ortiz Sobrinho; Pfeiffer, Maria Eulália Thebit

doi:10.5935/2359-4802.20180059

Cited by 2 publications

(2 citation statements)

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“…Rheumatic fever (RF) is a prevalent condition in developing countries, accounting for a cardiac mortality of rate 7.9% in Brazil (DATASUS). 1 Cases of rheumatic fever are often underdiagnosed and recognized only after permanent valve damage due to previous carditis. 2 Secondary prevention of RF aims to limit the development and/or progression of valvular lesions and their complications.…”

Section: Introductionmentioning

confidence: 99%

Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report

Salazar¹,

Romero²,

Lopes³

et al. 2022

International Journal of Cardiovascular Sciences

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Section: Introductionmentioning

confidence: 99%

Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report

Salazar¹,

Romero²,

Lopes³

et al. 2022

International Journal of Cardiovascular Sciences

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“…The Global Burden of Disease study estimated 10.5 million disability-adjusted life years and 319,499 deaths in 2015 due to RHD ( 1 ). In Brazil, the estimated annual incidence reaches 30,000 new cases per year, leading to a high cardiac mortality of −8% ( 2 – 4 ). Of note, RHD population has singular characteristics comparing to other etiologies of valvular heart disease.…”

Section: Introductionmentioning

confidence: 99%

Transcatheter Valve-in-Valve Procedures for Bioprosthetic Valve Dysfunction in Patients With Rheumatic vs. Non-Rheumatic Valvular Heart Disease

Lopes

Rosa

Palma

et al. 2021

Front. Cardiovasc. Med.

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Background: Bioprosthetic heart valve has limited durability and lower long-term performance especially in rheumatic heart disease (RHD) patients that are often subject to multiple redo operations. Minimally invasive procedures, such as transcatheter valve-in-valve (ViV) implantation, may offer an attractive alternative, although data is lacking. The aim of this study was to evaluate the baseline characteristics and clinical outcomes in rheumatic vs. non-rheumatic patients undergoing ViV procedures for severe bioprosthetic valve dysfunction.Methods: Single center, prospective study, including consecutive patients undergoing transcatheter ViV implantation in aortic, mitral and tricuspid position, from May 2015 to September 2020. RHD was defined according to clinical history, previous echocardiographic and surgical findings.Results: Among 106 patients included, 69 had rheumatic etiology and 37 were non-rheumatic. Rheumatic patients had higher incidence of female sex (73.9 vs. 43.2%, respectively; p = 0.004), atrial fibrillation (82.6 vs. 45.9%, respectively; p < 0.001), and 2 or more prior surgeries (68.1 vs. 32.4%, respectively; p = 0.001). Although, device success was similar between groups (75.4 vs. 89.2% in rheumatic vs. non-rheumatic, respectively; p = 0.148), there was a trend toward higher 30-day mortality rates in the rheumatic patients (21.7 vs. 5.4%, respectively; p = 0.057). Still, at median follow-up of 20.7 [5.1–30.4] months, cumulative mortality was similar between both groups (p = 0.779).Conclusion: Transcatheter ViV implantation is an acceptable alternative to redo operations in the treatment of patients with RHD and severe bioprosthetic valve dysfunction. Despite similar device success rates, rheumatic patients present higher 30-day mortality rates with good mid-term clinical outcomes. Future studies with a larger number of patients and follow-up are still warranted, to firmly conclude on the role transcatheter ViV procedures in the RHD population.

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Evolutive Study of Rheumatic Carditis Cases Treated with Corticosteroids in a Public Hospital

Cited by 2 publications

References 0 publications

Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report

Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report

Transcatheter Valve-in-Valve Procedures for Bioprosthetic Valve Dysfunction in Patients With Rheumatic vs. Non-Rheumatic Valvular Heart Disease

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