Association between Erectile Dysfunction and Quality of Life in Patients with
            Coronary Artery Disease

Tabosa, André Ricardo dos Santos; Oliveira, Dinaldo Cavalcanti de; Stangler, Vitor H.; Araüjo, Henrique; Nunes, Vítor; Gadelha, Maria Isabel; Oliveira, Danilo; Tenório, Emmanuelle

doi:10.5935/2359-4802.20170042

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…The results obtained are similar to the data of one of the first studies conducted by Montorsi and co-authors, which showed that ED prevalence is 42–57% in patients with CVD [ 29 ]. Other studies have reported that the prevalence of ED among such patients varies from 47 to 75% or even in a wider range—24–89% [ 36 , 37 , 38 ]. This difference in prevalence is explained by the fact that different studies analyse very different populations, define ED differently, have different methods of diagnosing CVD and patients have various co-morbidities and/or take various drugs that may affect erectile function differently [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Erectile Dysfunction and Its Association with Cardiovascular Risk Factors in Patients after Myocardial Infarction

et al. 2021

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Background and Objectives: This study estimates the prevalence and severity of erectile dysfunction and its association with cardiovascular risk factors in patients after a myocardial infarction. Materials and Methods: This study included men aged 35–80 years, diagnosed with myocardial infarction and examined in the Department of Preventive Cardiology of Vilnius University Hospital Santaros Klinikos between 2016 and 2020. Anthropometric characteristics, blood pressure, lipid profile, blood glucose levels and prevalence of cardiovascular risk factors were evaluated. The International Index of Erectile Function-5 was used to assess patients’ erectile function. Results: A total of 171 patients were analysed. The mean age was 57.6 ± 8.8 years. Of the patients, 42.1, 25.1 and 11.7% had three, four and five established cardiovascular risk factors, respectively. Of the patients, 100% were diagnosed with dyslipidaemia, 90.0%—arterial hypertension, 14.6%—diabetes, 23.3%—smoking, 43.7%—positive familial history and 54.5%—insufficient physical activity. The overall prevalence of erectile dysfunction was 62%. It was scored mild in 37.4%, mild-to-moderate—15.2%, moderate—5.3% and severe in 4.1% of the patients. The mean age was significantly different between severity groups (p < 0.001). The study demonstrated a negative correlation between age and total score of the questionnaire (r = −0.308, p < 0.001). Arterial hypertension was more frequent in the patients with erectile dysfunction (p = 0.02). Other cardiovascular risk factors were distributed similarly. Conclusions: Erectile dysfunction is common in patients after a myocardial infarction and its severity is age dependent. The prevalence of cardiovascular risk factors is high, with arterial hypertension significantly more frequent in patients with erectile dysfunction.

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Section: Discussionmentioning

confidence: 99%

The Prevalence of Erectile Dysfunction and Its Association with Cardiovascular Risk Factors in Patients after Myocardial Infarction

et al. 2021

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“…Predominantly a vascular disorder, ED affects both physical and psychological health, having a direct impact on men's life quality and their sexual partners, mainly due to a reduction in self-esteem and impairment of interpersonal relationships (Boddi et al, 2015;Nguyen et al, 2017;Burnett et al, 2018). It mainly affects men after 40 years of age and it has estimated that over 150 million worldwide have some degree of this dysfunction (Ayta et al, 1999;Grover et al, 2006;Riedner et al, 2011;Tabosa et al, 2017). However, even if the increasing in cases with aging is evident, ED is not an inevitable consequence of aging, which makes it possible to increase the estimate of the average world prevalence (Seftel, 2011;Shamloul and Ghanem, 2013;Yafi et al, 2016;Gabrielson et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review

et al. 2020

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Erectile dysfunction (ED) is a prevalent condition, especially in men over 40 years old, characterized by the inability to obtain and/or maintain penile erection sufficient for satisfactory sexual intercourse. Several psychological and/or organic factors are involved in the etiopathogenesis of ED. In this context, we gathered evidence of the involvement of Largeconductance, Ca 2+-activated K + channels (BK Ca), Small-conductance, Ca 2+-activated K + channels (SK Ca), KCNQ-encoded voltage-dependent K + channels (K V 7), Transient Receptor Potential channels (TRP), and Calcium-activated Chloride channels (CaCC) dysfunctions on ED. In addition, the use of modulating agents of these channels are involved in relaxation of the cavernous smooth muscle cell and, consequent penile erection, suggesting that these channels are promising therapeutic targets for the treatment of erectile dysfunction.

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Prevalence of Erectile Dysfunction among Patients with Coronary Artery Disease

Mohamed Abd Elsamie,

Abou Khodair,

Bashandy

et al. 2024

Andrologia

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Both coronary artery disease (CAD) and erectile dysfunction (ED) are widespread illnesses that frequently coexist. Numerous triggering risk factors and pathophysiological mechanisms contribute to both diseases. Penile color Doppler ultrasound can serve as a crucial tool to evaluate penile arterial blood flow. Therefore, this study aims to assess the ED prevalence in CAD patients, to determine the socioeconomic and clinical profiles of the population, and to define risk factors of their development. The cross-sectional study included 100 male patients who were admitted to the coronary angiography (CAG) unit. Patients were asked if they had ED, and if present, it was graded using the International Index of Erectile Function 5. Right and left cavernosal arteries were examined using color Doppler and erection hardness to assess the peak systolic velocity (PSV) and end-diastolic velocity. Among the 52 cases that suffered from ED, most of the cases had mild grades (38.5%). All cases without ED (100%) had penile artery Doppler PSV findings ≥30 (cm/s) with an average Doppler PSV of 48.02 ± 7.49 cm/s for the right cavernosal arteries and 47.4 ± 7.17 cm/s for the left cavernosal arteries. Yet, 71.2% of cases with ED had penile artery Doppler PSV findings <30 (cm/s) with an average Doppler PSV of 29.1 ± 7.57 cm/s for the right cavernosal arteries and 28.69 ± 7.11 cm/s for the left cavernosal arteries. Furthermore, by CAG, 50% of cases without ED had blockage not necessitating a coronary intervention (no significant disease) compared to 25% of cases with ED. There was positive correlation between advanced grade of ED and age (r = 0.327, P <0.001), hypertension (r = 0.213, P = 0.033), DM (r = 0.253, P = 0.011), smoking (r = 0.202, P = 0.044), and severity of CAD (r = 0.332, P <0.001). Patients with multivessel CAD have a significantly higher incidence and more severity of ED. Moreover, pathological penile vessels PSV (<25 or <30 cm/s) via Doppler ultrasound is mostly valuable as a noninvasive tool to define ED attributable to vascular impairment that may be antecedent to atherosclerosis in the coronary vessels.

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Association between Erectile Dysfunction and Quality of Life in Patients with Coronary Artery Disease

Abstract: Background: Erectile dysfunction (ED) and coronary artery disease (CAD) share the same risk factors and the associations between ED, quality of life (QoL) and CAD have been the subject of recent studies.

Cited by 3 publications

References 27 publications

The Prevalence of Erectile Dysfunction and Its Association with Cardiovascular Risk Factors in Patients after Myocardial Infarction

The Prevalence of Erectile Dysfunction and Its Association with Cardiovascular Risk Factors in Patients after Myocardial Infarction

Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review

Prevalence of Erectile Dysfunction among Patients with Coronary Artery Disease

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