Cardiopulmonary Exercise Testing in Patients With Left Bundle Branch Block and
            Preserved Ejection Fraction

Barros, Milena dos Santos; Amorim, Rívia Siqueira; Rocha, Romerito Oliveira; Melo, Enaldo Vieira de; Barreto‐Filho, José Augusto; Sousa, Antônio Carlos Sobral; Meneghelo, Romeu Sérgio; Oliveira, Joselina Luzia Menezes

doi:10.5935/2359-4802.20170018

Cited by 1 publication

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References 15 publications

(27 reference statements)

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“…Along this line, CPET, with incremental workload and symptom‐limited exercise testing, is considered the gold standard when studying maximal aerobic capacity in the general population 8 . However, regarding physical performance in the LBBB population, only a previous cross‐sectional study conducted by Barros et al 9 evaluated the effects of this ECG conduction disturbance in 26 subjects with an LVEF > 50% and mainly a sedentary lifestyle. In congruence with our results, the authors reported a reduced baseline pp‐peakVO 2 (87.2%) with a mean VE/VCO 2 slope <30.…”

Section: Discussionmentioning

confidence: 99%

Maximal functional capacity in subjects with isolated left bundle branch block: A pilot study

Palau

Méndez²,

Santas

et al. 2023

Clinical Cardiology

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Background: Left bundle branch block (LBBB) has been commonly associated with adverse cardiovascular (CV) events, but the effect of an isolated LBBB on maximal functional capacity is not well characterized.Objective: To evaluate maximal functional capacity in adults with isolated LBBB and compare it to healthy population-derived predicted values (adjusted for sex, age, weight, and height).Methods: This descriptive pilot study included subjects with isolated LBBB derived from outpatient clinics of two academic hospitals. All subjects underwent maximal cardiopulmonary exercise testing (CPET) and a Global Physical Activity Questionnaire (GPAQ). The primary outcome was to evaluate maximal functional capacity according to population-derived predicted values of peak oxygen consumption (peakVO 2 ): pp-peakVO 2 . The secondary outcome was to report adverse CV events (CV deaths or hospitalizations) at follow-up.Results: A total of 27 (18 women and 9 men) participants were included. The median (interquartile range) age of the sample and time to screening from the first LBBB diagnosis were 62 (51−71) and 3.4 (1.1−8.4) years, respectively. The results of the GPAQ score showed that 19 patients were highly active, and 8 were moderately active. The median of peakVO 2 and pp-peakVO 2 were 19.3 (15−22.5) ml/kg/min and 88% (79.3%−104.4%), respectively. There were no adverse CV events at a median follow-up after CPET of 3.1 (2.7−3.4) years. Conclusion:In this pilot study, adults with isolated LBBB showed reduced maximal functional capacity, despite the absence of cardiac disease and a baseline moderate to highly active lifestyle.

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Section: Discussionmentioning

confidence: 99%

Maximal functional capacity in subjects with isolated left bundle branch block: A pilot study

Palau

Méndez²,

Santas

et al. 2023

Clinical Cardiology

View full text Add to dashboard Cite

show abstract

Cardiopulmonary Exercise Testing in Patients With Left Bundle Branch Block and Preserved Ejection Fraction

Abstract: Background: Left bundle branch block (LBBB) has prognostic significance in patients with congestive heart failure. However, its influence is not well established in patients with preserved systolic ventricular function.

Cited by 1 publication

References 15 publications

Maximal functional capacity in subjects with isolated left bundle branch block: A pilot study

Maximal functional capacity in subjects with isolated left bundle branch block: A pilot study

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