Chemotherapy-induced peripheral neuropathy: review for clinical practice

Simão, Delma Aurélia da Silva; Murad, Munir; Martins, Carolina Castro; Fernandes, Viviane Cristina; Captein, Karine Marley; Teixeira, Antônio Lúcio

doi:10.5935/1806-0013.20150043

Cited by 16 publications

(22 citation statements)

References 40 publications

(50 reference statements)

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“…Essas classes de quimioterapia, pelos efeitos terapêuticos que possuem, embora causem efeitos adversos, como a NPIQ, dificilmente podem ser substituídas por outras classes sem que a eficácia terapêutica no controle e cura da doença não seja comprometida. A NPIQ é um efeito adverso SIMÃO et al, 2015).…”

Section: Resultsunclassified

Perfil Clínico-Epidemiológico E Os Principais Diagnósticos De Crianças Internadas Em Um Hospital Pediátrico

Pereira¹,

Câmara²,

Lima³

et al. 2021

Medicina Integral: Desafios Enfrentados No Ambiente Hospitalar

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Pressure injury develops from prolonged pressure on the surface of the skin or soft tissues, making it difficult or impeding tissue perfusion, causing underlying tissue damage and especially bone prominence. The purpose of the present study was to raise risk factors associated with the occurrence of pressure injury and the possibility of nurses acting on their prevention according to the literature. DEVELOPMENT: The present study uses as integrative literature review method, performed through a search in the Virtual Health Library (VHL) in the databases of Lilacs and Medline and Scielo (Scientific Electronic Library Online) using the intersections of the descriptors "Pressure Injury", "Incidence", "Hospital". For the construction of this article, the following question was applied: what are the risk factors for the occurrence of pressure injury in the hospital environment and the nurse's role in relation to this problem? Among the main factors associated with the occurrence of pressure injury described in the analyzed studies were: skin exposure, excessive humidity, pressure on prominence, loss of sensation, immobility, friction and shear. In addition, studies have shown that the incidence of such injuries occurs mainly in critically ill male patients over the age of 60 and in longer hospitalizations. CONCLUSION: This study presented the risk factors for the occurrence of pressure injury, contributing to the understanding of the multicausality in the onset of this condition. It was found that some care can reduce the appearance of lesions, especially when directed to the environment, to extrinsic factors.

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Section: Resultsunclassified

Perfil Clínico-Epidemiológico E Os Principais Diagnósticos De Crianças Internadas Em Um Hospital Pediátrico

Pereira¹,

Câmara²,

Lima³

et al. 2021

Medicina Integral: Desafios Enfrentados No Ambiente Hospitalar

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“…According to the International Association for the Study of Pain (IASP), neuropathic pain is “the pain caused by injury or disease of the somatosensory system”. It is present in 40% of cancer patients, and CIPN patients have a three-fold greater chance of developing neuropathic pain, a condition that is characteristic of CIPN 30 . This finding supports the importance of identifying some other objective measure of CIPN symptoms.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture in adults with Chemotherapy-Induced Peripheral Neuropathy: a systematic review

Baviera

Olson

Paula

et al. 2019

Rev. Latino-Am. Enfermagem

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Objective: to analyze and synthesize knowledge about the effect of acupuncture on chemotherapy-induced peripheral neuropathy symptoms in adults with cancer. Method: the method used was a Systematic Review. Potential articles were identified by searching in the PubMed of National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Embase, Cochrane Central and Scopus. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses strategy, 607 articles were identified. After removing the duplicates, all titles and abstracts were reviewed, and seven articles were selected for full review. After the full review, five studies were selected for inclusion. Results: of the five articles included, four were cohort studies and one was a quasi-experimental study. All articles showed that acupuncture was associated with an improvement in the peripheral neuropathy, but the type of protocol, use of medications, time of treatment, and different outcome measures made it difficult to compare the studies. Conclusion: the use of acupuncture appears to be associated with an improvement in the symptoms of chemotherapy-induced peripheral neuropathy and has no side effects. In order to improve the evidence about benefits associated with acupuncture, more experimental studies using both subjective and objective measures are needed.

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“…This may accredited to the effect of chemotherapeutic agents that interfere with axonal transport, target the sensory cell bodies and nerve axons, and induce neuronal cell death. [28] In this respect studies by Cavaletti and Marmiroli, 2015; Dermitzakis, Kimiskidis & Lazaridis, 2016 and Boland, Sherry, and Polomano, 2017 [29][30][31] reported that, clinically, CIPN presents as deficits in sensory, motor, and autonomic function but sensory symptoms are far more common than motor or autonomic.…”

Section: Discussionmentioning

confidence: 99%

Chemotherapy-induced peripheral neuropathy and its association with quality of life among cancer patients

Mohamed

Mohamed²

2019

JNEP

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Background and objective: Chemotherapy-induced peripheral neuropathy (CIPN) is a common incapacitating complication of various chemotherapeutic agents that severely impact the patient’s quality of life. Most of patients treated with anticancer agents develop CIPN early after treatment and may necessitate dose modification or termination, which can increase cancer-related morbidity and mortality. Aim: investigate the Chemotherapy-Induced Peripheral Neuropathy and its Association with Quality of Life among Cancer patients.Methods: A descriptive study design was applied in this study, on a purposeful sample of 250 adult patients diagnosed with chemotherapy induce peripheral nephropathy. The study instruments were the demographic and medical history questionnaire, PNQ, EORTC CIPN20 and EORTC30.Results: Symptoms severities mean score is 5.58 ± 2.97. Sensory neuropathy registered the highest mean at 21.23 points, followed by motor (17.33) and autonomic (5.11). About one quarter of participants reported poor global quality of life. Poor physical function was reported by 22.3% of all participants. Fatigue, pain and insomnia were the most common symptoms suffered by patients. There is a relation between CIPN and duration of cancer diagnosis, type of cancer, intervention, gender, and other condition.Conclusions: CIPN is the furthermost common complication of chemotherapy that affects patient’s QoL. Assessment of chemotherapy-related peripheral neuropathy helps clinicians to develop and evaluate much needed targeted therapies and to help improving QoL.

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Chemotherapy-induced peripheral neuropathy: review for clinical practice

Cited by 16 publications

References 40 publications

Perfil Clínico-Epidemiológico E Os Principais Diagnósticos De Crianças Internadas Em Um Hospital Pediátrico

Perfil Clínico-Epidemiológico E Os Principais Diagnósticos De Crianças Internadas Em Um Hospital Pediátrico

Acupuncture in adults with Chemotherapy-Induced Peripheral Neuropathy: a systematic review

Chemotherapy-induced peripheral neuropathy and its association with quality of life among cancer patients

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