Sex Differences in Mortality After CABG Surgery

Abstract

INTRODUCTIONNumerous studies have shown that women undergoing coronary artery bypass graft surgery present higher mortality rate during hospitalization, and often complications when compared to men.OBJECTIVETo compare the mortality of men and women undergoing coronary artery bypass graft surgery and identify factors related to differences occasionally found.METHODSRetrospective cohort study conducted with 215 consecutive patients who underwent coronary bypass surgery.RESULTSWomen had a higher average age. Low body surface and dyslipidemia were more prevalent in women (1.65 vs. 1.85, P <0.001: 53% vs. 30%, P =0.001), whereas history of smoking and previous myocardial infarction were more prevalent in men (35% vs.14.7%, P =0.001; 20% vs. 2.7%, P =0.007). Regarding complications in the postoperative period, there was a higher rate of blood transfusions in women. The overall mortality rate was 5.6%, however there was no statistically significant difference in mortality between men and women. It was observed that among the patients who died, the average body surface area was lower than that of patients who did not have this complication.CONCLUSIONThere was no difference in mortality between the sexes after coronary artery bypass graft in this service.

Are the Early Postoperative Outcomes of Coronary Artery Bypass Grafting Surgery in Elderly Women Worse Compared to Men's?

“…There is also inconsistency between gender difference and postoperative outcomes following CABG in the previous studies when examined and compared with each other. In many studies female gender was found associated with worse postoperative outcomes after CABG surgery [ 8 - 11 ] , while in some other studies which especially had the propensity-matching for the adjustment of risk factors, demonstrated that the outcomes in females were similar to their matched male counterpart following CABG [ 12 - 15 ] . Thus, the impact of gender difference on postoperative outcomes after CABG is a debated topic of ongoing relevance.…”

Gender-Related Discrepancies in Short-Term Outcomes in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting Surgery

“…Studies on gender differences after OPCAB surgery are scarce [ 16 , 17 , 18 , 19 , 20 ]. Previous retrospective trials have shown that female gender might be an independent risk factor for operative mortality [ 14 , 23 ]. Similarly, Alam et al [ 24 ] found increased operative and 30-day mortality rates in females compared to males after bypass surgery.…”