Cytomorphological analysis of cervical cytological smears of women aged over 60
            years

Backes, Luana Taís Hartmann; Mezzomo, Lisiane Cervieri; Buffon, Andréia; Calil, Luciane Noal

doi:10.5935/1676-2444.20190016

Cited by 3 publications

(2 citation statements)

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“…In view of the above, we highlight the importance of following up women diagnosed with HPV, especially those at high-risk, considering that It are in conditions of greater social vulnerability [ 16 ]. Weber [ 17 ] and Backes [ 18 ] found a frequency of atypia in their studies carried out in the general population of 3 and 4% respectively, being, therefore, lower in relation to the findings of the research demonstrated. The rates identified in our studies, 4.54% ( n = 22) gypsy women and 6.50% ( n = 123) quilombola women being in convergence with this cited evidence.…”

Section: Discussionmentioning

confidence: 69%

Frequency of human papilomavirus and associated factors in gypsy and quilombola women

et al. 2023

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Background The prevalence of Human Papillomavirus (HPV) infection in the general population is widely known, however, there are still few studies related to this infection in minority groups, Thus, the objective is to analyze the frequency of human papillomavirus and associated factors in quilombola and gypsy women. Methods Cross-sectional research with 145 quilombola and gypsy women from Caxias, Maranhão. Two Pap smear collections were performed and a questionnaire with 46 questions was applied between January, 2020 and March, 2021. Descriptive analysis and Odds Ratio with 95% confidence interval were performed. The research was approved by the ethics committee. Results There were 09 cases of atypia. The frequency of human papillomavirus was 41.37%, with a higher risk in quilombolas 55 (91.70%). Multiple infections were prevalent (53%) with high-risk genotypes 21 (35%). Types 16 and 18 together accounted for 42.85% of cases. Conclusions The frequency of human papillomavirus infection was higher than those recorded in the Northeast and Brazil, and therefore type 16 predominated. Due to limitations, the virus lineages and sublineages were not evaluated. Quilombola women had a higher rate of infection than gypsies.

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Section: Discussionmentioning

confidence: 69%

Frequency of human papilomavirus and associated factors in gypsy and quilombola women

et al. 2023

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“…Many studies have demonstrated a low detection rate of dysplasia in the histologic follow-up of post-menopausal women with cytological reports of atypia or atypical squamous cells of undetermined significance (ASC-US). The factors that cause misinterpretation include hormonal changes, inflammation, reactive metaplasia, air drying, and sampling problems [ 5 6 7 8 ]. However, the extent of misinterpretation of histological outcomes from menopausal status is not well-documented, and there are no specific guidelines for menopausal status-dependent management.…”

Section: Introductionmentioning

confidence: 99%

Factors Associated with Cyto-Histological Misinterpretation of Cervical Smear according to Menopausal Status

Choi

Lee

et al. 2022

J Menopausal Med

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Objectives This study aimed to compare histological outcomes between pre-menopausal and post-menopausal women with cervical cytological abnormalities and to investigate the clinical factors affecting the misinterpretation of cytology and histology. Methods We conducted a retrospective analysis of 599 patients with abnormal cervical cytology who underwent loop electrosurgical excision procedure (LEEP) between January 2010 and May 2019. Baseline characteristics were collected, including age, height, weight, body mass index, gravity, parity, and menopausal status. In total, 477 pre-menopausal women and 122 post-menopausal women were recruited. Results Atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions were cytologically observed in 73.4% (135/184) of the pre-menopausal women, which were high-grade lesions confirmed by LEEP. In post-menopausal patients with cytology results that cannot exclude high-grade squamous intraepithelial lesions (ASC-H) or high-grade squamous intraepithelial lesions (HSIL), 27.0% (24/89) were confirmed to have histologically low-grade lesions. High-risk HPV (hrHPV) prevalence in abnormal cervical smears was 92.2%. Moreover, other hrHPVs had a higher risk of unexpected histological outcomes unrelated to cytologic results. Conclusions Menopausal status and HPV infection are associated with misinterpretation of cervical cytology and histology. Therefore, the menopausal status of patients should be considered for the management of cervical cytology, and primary co-testing is recommended to identify women at risk of cervical abnormalities.

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Citopatológico do colo uterino e adequabilidade da amostra: ensaio clínico randomizado controlado

Freitas¹,

Nicolau²,

Lima³

et al. 2023

Acta Paulista De Enfermagem

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Cytomorphological analysis of cervical cytological smears of women aged over 60 years

Cited by 3 publications

References 0 publications

Frequency of human papilomavirus and associated factors in gypsy and quilombola women

Frequency of human papilomavirus and associated factors in gypsy and quilombola women

Factors Associated with Cyto-Histological Misinterpretation of Cervical Smear according to Menopausal Status

Citopatológico do colo uterino e adequabilidade da amostra: ensaio clínico randomizado controlado

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