Mucocutaneous Kaposi’s sarcoma in an HIV-positive patient: diagnosis and treatment

Carvalho, Laura Priscila Barboza De; Lucena, Laudenice P.; Honorato, Maria Cristina T. M.; Andrade, Gilka Soares Sampaio; Freitas, Roseana A.

doi:10.5935/1676-2444.20160033

Cited by 4 publications

(23 citation statements)

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“…Management may depend upon a variety of factors including results of staging and comorbilities. Local measures such as intralesional vinblastine or systemic administration of cytotoxic chemotherapy for disseminated disease are all possibilities [20].…”

Section: Discussionmentioning

confidence: 99%

HIV-Associated Oral Kaposi Sarcoma: Case Report and Literature Review

Mdc¹,

Caixeirinho²,

Matos³

et al. 2019

Journal of Case Reports and Studies

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Kaposi sarcoma (KS) is an angioproliferative polymorfic disorder that might be associated with human immunodeficiency virus (HIV) infection. In this clinical form, oral manifestation is particularly common and, sometimes, the first manifestation of the retroviral infection. In those cases, KS diagnosis is fundamental as the treatment is based in HIV infection control through an advisable multidisciplinary approach.

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Section: Discussionmentioning

confidence: 99%

HIV-Associated Oral Kaposi Sarcoma: Case Report and Literature Review

Mdc¹,

Caixeirinho²,

Matos³

et al. 2019

Journal of Case Reports and Studies

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show abstract

“…OKS lesions initially manifest as a proliferation of small veins and capillaries around one or more dilated vessels may be associated with bleeding, pain, and functional interferences caused by the tumour [23], [28], [29]. OKS lesions are mostly observed in young adult patients, often affecting mucous, skin, and internal organs [23], [28], [29].…”

Section: A the Course Of The Diseasementioning

confidence: 99%

“…It has an aggressive clinical course [4], [28], [29]. KS is reported to be the most prevalent type of cancer in HIV+ patients that have not received treatment, and it is associated with the infection by HHV-8 [29]- [31].…”

Section: A the Course Of The Diseasementioning

confidence: 99%

“…OKS lesion is initially a flat brown or reddish-purple macule that does not blanch with pressure and generally begins as multiple lesions or as a single lesion of the oral mucosa [29], [32]. The lesion may develop into plaques or nodules, and further disseminating to lymph nodes and organ systems as the malignancy progresses and tends to be spread, multiply in number, become more nodular or coalesce in association with immunological deterioration and the drop in the count of CD4 cells [27], [29], [32].…”

Section: A the Course Of The Diseasementioning

confidence: 99%

“…The differential diagnosis of KS includes and for early lesions can be included lesions such as benign vascular proliferation like hemangioma, bacillary angiomatosis, and pyogenic granuloma [18], [29], [30], [32].…”

Section: Differential Diagnosismentioning

confidence: 99%

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Kaposi's Sarcoma and Lymphoedema in a HIV Sero-positive Patient: A Case Report and Literature Review

Turton

Reddy²,

Turton³

2021

EJDENT

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Kaposi sarcoma (KS) is one of the most common neoplasms diagnosed in HIV- seropositive subjects. KS is an angioproliferative disorder of endothelial origin and is a locally aggressive multicentric mucocutaneous malignant neoplasm. Aggressive HIV-KS is associated with increased HHV8 viral load, disseminated lesions, and intraoral exophytic lesions, and may also present with facial lymphoedema which may be life-threatening or mild. A 26 -year-old, male, presented with severe oral pain and facial swelling. He had multiple oral lesions and an incisional biopsy confirmed Kaposi sarcoma. A multiple site incisional biopsy and immunohistochemistry for HHV8 was done and based on the clinical, histopathological, and immunohistochemical results a diagnosis of HIV associated oral and cutaneous KS with severe lymphoedema was confirmed. This aim of this case presentation is to describe a case of immunodeficiency virus-related lymphadenitis, oral and cutaneous KS associated with the complication severe lymphoedema in a HIV infected patient who was not on HAART therapy for three years after being diagnosed with HIV.

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Relação da alta incidência do sarcoma de Kaposi em pacientes soropositivos para o HIV/AIDS

Silva

Pereira

Silva

et al. 2022

RSD

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O HIV é o vírus da imunodeficiência humana que causa a AIDS, síndrome da imunodeficiência adquirida, e após sua evolução e alto índice de casos no mundo, fez-se presente concomitantemente a esses pacientes o Sarcoma de Kaposi, que é uma doença que age nos vasos linfáticos, e que pode atingir desde à cavidade oral até outros e vários órgãos. Sendo assim, o presente trabalho trata-se de uma revisão integrativa, descritivo-explicativo de caráter básico sobre a relação da alta incidência do sarcoma de Kaposi em pacientes soropositivos para o HIV. O trabalho tem como objetivo descrever os mecanismos do HIV quanto à suas células de defesa e variação do TCD4+, o papel do HHV-8 para com a doença e também a ação da terapia antirretroviral nesse contexto. Outrossim, analisar a interação dos mecanismos citados para a conclusão da etiologia e além disso, a análise do tratamento e prognóstico da doença.

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Mucocutaneous Kaposi’s sarcoma in an HIV-positive patient: diagnosis and treatment

Cited by 4 publications

References 0 publications

HIV-Associated Oral Kaposi Sarcoma: Case Report and Literature Review

HIV-Associated Oral Kaposi Sarcoma: Case Report and Literature Review

Kaposi's Sarcoma and Lymphoedema in a HIV Sero-positive Patient: A Case Report and Literature Review

Relação da alta incidência do sarcoma de Kaposi em pacientes soropositivos para o HIV/AIDS

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