Kinetics of the expressions of radiation-induced plasma proteins of the cardiac territory in electrophoresis

Reversing radiation-induced immunosuppression using a new therapeutic modality

“…Furthermore, recent studies have shown that there are other key players involved in radiation associated damage and targeting them using conventional approaches such as recombinant proteins or small molecule drugs is time consuming, laborious, expensive and ultimately not feasible. 2,3,[21][22][23][24][25][26][27][28][29][30]5,[11][12][13][14][18][19][20] To address the limitations of the existing approaches, we have developed a new approach to highthroughput drug-discovery, target validation, and lead molecule identification using nucleic acidbased molecules, called Nanoligomer™, that are rationally designed and synthesized to up-or downregulate expression of target gene at the messenger RNA (mRNA) or protein level. Furthermore, it alters related gene network targets ultimately resulting in pathway modulation.…”

Reversing Radiation-Induced Immunosuppression Using a New Therapeutic Modality

“…Furthermore, recent studies have shown that there are other key players involved in radiation associated damage and targeting them using conventional approaches such as recombinant proteins or small molecule drugs is time consuming, laborious, expensive and ultimately not feasible. 2,3,[21][22][23][24][25][26][27][28][29][30]5,[11][12][13][14][18][19][20] To address the limitations of the existing approaches, we have developed a new approach to highthroughput drug-discovery, target validation, and lead molecule identification using nucleic acidbased molecules, called Nanoligomer™, that are rationally designed and synthesized to up-or downregulate expression of target gene at the messenger RNA (mRNA) or protein level. Furthermore, it alters related gene network targets ultimately resulting in pathway modulation.…”