Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder

Abrantes, Carlos; Silva, Mário Rui; Oliveira, Rui Caetano; Eloy, Catarina; Cipriano, Maria Augusta; Castro, Lígia

doi:10.5935/1676-2444.20150065

Cited by 4 publications

(6 citation statements)

References 15 publications

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“…Fonte: Os autores. v. 2 A histologia relevou uma proliferação de células fusiformes com infiltrado inflamatório de linfócitos, plasmócitos e estroma rico em colágeno, compatível com tumor miofibroblástico inflamatório. Após nove meses, o doente permanece assintomático, com testes de função hepática com valores normais e sem sinais imagiológicos de recidiva.…”

Section: Resultsunclassified

“…Essa formação tecidual anormal recebe o nome de neoplasia e é composta por tipos celulares específicos (miofifroblásticas e fibroblásticas) somados a um acúmulo de glóbulos brancos. Devido a estrutura da quinase nessa formação é possível diferenciá-la de outras patologias esclerosantes e de pseudotumores e classificá-la, portanto, como uma verdadeira neoplasia 2 . Este agravo acomete principalmente crianças e jovens adultos e o seu sítio de acometimento dá-se em qualquer órgão e tecido, no entanto, observa-se maior frequência em tecidos moles abdominais, mesentério, omento, retroperitônio e pelve.…”

Section: Introductionunclassified

“…Quanto aos órgãos mais acometidos, podemos citar o fígado e o pulmão, sendo este último relacionado muitas vezes com a co-infecção pela Mycobacterium tuberculosis, responsável pela Tuberculose 3 . O tumor miofibroblástico inflamatório gastrointestinal (TMIG) é uma condição rara, no entanto, com prognóstico que carece de atenção por tratar-se de lesões de grande extensão e com diagnóstico inicial dificultado 2 .…”

Section: Introductionunclassified

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Tumor miofibroblástico inflamatório gastrointestinal: uma revisão da literatura

Vitali de Mattos Pereira,

De Carvalho Leite

2023

RBPS

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Introdução: O tumor miofibroblastico inflamatório (TMI) refere-se a uma proliferação celular anormal com a presença de um infiltrado inflamatório que pode acometer diferentes órgão e tecidos e tem não tem gravidade, etiologia, diagnóstico e tratamento pré-estabelcidos. Objetivos: identificar o que a literatura mais atual trás sobre o tumor miofibroblástico inflamatório gastrointestinal e suas implicações. Métodos: Trata-se de um estudo descritivo de revisão de literatura, em 3 (três) bases de dados online: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS); Scientific Electronic Library Online (SciELO); Medical Literature Analysis and Retrievel System Online (MEDLINE) com o descritor e suas combinações nas línguas portuguesa e inglesa:(Inflammatory myofibroblastic tumor gastrointestinal). Resultados: Foram analisados nessa revisão 05 artigos dentro dos critérios de inclusão. Conclusão: Concluiu-se com este estudo que o TMI gastrointestinal é uma condição rara, mas com capacidade de lesões extensas e que carece de estudos e pesquisas mais especificas, tendo em vista sua gravidade e prognóstico.

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Section: Resultsunclassified

Section: Introductionunclassified

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Tumor miofibroblástico inflamatório gastrointestinal: uma revisão da literatura

Vitali de Mattos Pereira,

De Carvalho Leite

2023

RBPS

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“…The term inflammatory pseudotumour has been used to describe an inflammatory or fibrosing tumoural process of undetermined cause that may involve a variety of organ systems, including the lungs, spleen, liver, lymph nodes, pancreas and extrahepatic bile duct with potential for recurrence and persistent local growth [1,2]. There is a limited number of case reports in the literature indicating gallbladder location [3,4]. Inflammatory pseudotumour appear to be more common in non-European populations.…”

Section: Discussionmentioning

confidence: 99%

A case of inflammatory pseudotumour of the gallbladder presenting as a big mass of uncertain behavior

et al. 2020

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Background: Inflammatory pseudotumour has been used to describe an inflammatory or fibrosing tumoral process of an undetermined cause that may involve a variety of organ systems, including the lungs, spleen, liver, lymph nodes, pancreas and extrahepatic bile duct with potential for recurrence and persistent local growth. In this article, we report a patient with a big mass of uncertain nature and behavior. Case presentation: A 60-year-old woman presented with a 1-week history of abdominal pain, fever and jaundice. Six months before she had had right upper quadrant pain that was interpreted as biliary colic. A contrast-enhanced CT scan showed a big mass of soft tissue with diffuse infiltration of the gallbladder, displacement of the transverse colon, hepatic flexure and duodenum. For diagnostic distinction between a chronic inflammatory disease or a neoplasm, exploratory laparotomy was required. Intraoperative exploration disclosed a big mass of hard texture involving the gallbladder, with multiple concrements, hepatoduodenal ligament, right and transverse mesocolon, stomach and duodenum. Cholecystectomy was performed, preserving adjacent organs with macroscopic desmoplastic reaction. Histopathologic examination of the gallbladder showed a spindle cell proliferation with diffuse chronic inflammatory infiltrate of lymphocytes, plasma cells and hyalinized fibrous stroma. No vascular invasion or cellular atypia were evident. Conclusion: Inflammatory pseudotumour is a rare condition and diagnostic distinction from a chronic inflammatory disease or other neoplasm is only possible by histopathologic examination. There is a limited number of case reports in the literature indicating tumor location in the gallbladder.

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“…As stated before, most cases occur in the small bowel [9] and stomach [10], but any part of the GI tract may be affected; even in the gallbladder, according to case reports [11]. Clinical features are variable, from abdominal pain to obstruction.…”

Section: Inflammatory Myofibroblastic Tumormentioning

confidence: 94%

Mesenchymal Tumors of the Gastrointestinal Tract—Beyond GIST—A Review

Gama,

Oliveira

2024

Gastrointestinal Disorders

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Sarcomas are rare lesions and encompass a wide variety of entities, depending on their nature. In recent years new entities have been described and new knowledge, especially that provided by molecular studies, has been increasing. This makes it very difficult to be updated with all the described entities, since only some of the centers have the desired ancillary studies for the correct diagnosis. Some lesions are extremely rare and may appear once or twice during the lifetime of a general pathologist. When we refer to sarcomas of the gastrointestinal tract, the gastrointestinal stromal tumor (GIST) is the most well-known lesion that the pathologist will most frequently find in daily practice. This paper aims to comprehensively review the sarcomas associated with the gastrointestinal tract, emphasizing histopathology and going beyond GIST. This review highlights the histopathology of rare types of sarcomas so it may increase awareness of common and rare lesions, prompting an easy and effective diagnosis.

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Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder

Cited by 4 publications

References 15 publications

Tumor miofibroblástico inflamatório gastrointestinal: uma revisão da literatura

Tumor miofibroblástico inflamatório gastrointestinal: uma revisão da literatura

A case of inflammatory pseudotumour of the gallbladder presenting as a big mass of uncertain behavior

Mesenchymal Tumors of the Gastrointestinal Tract—Beyond GIST—A Review

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