New red blood cell and reticulocyte parameters and reference values for healthy individuals and in chronic kidney disease

Scherer, Patrícia S.; Moraes, Daniela; Munhoz, Terezinha P.; Sgnaolin, Vanessa

doi:10.5935/1676-2444.20150014

Cited by 6 publications

(3 citation statements)

References 16 publications

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“… 19 , 20 , 21 Reference intervals for the RET-He have already been determined by other authors. 17 , 22 , 25 , 26 The range found in the present study, that of between 29.75pg and 38.24pg, is consistent with the range established by Scherer et al, who proposed a range of 30.30pg to 36.96pg for a group of healthy patients. 26 Furthermore, the range determined is also in accordance with a report by Levy et al, who proposed a 31.2-pg cut-off value to distinguish iron deficiency from non-iron deficiency.…”

Section: Discussionsupporting

confidence: 93%

Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women

Bó

Fragoso

Farias

et al. 2023

Hematology, Transfusion and Cell Therapy

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Section: Discussionsupporting

confidence: 93%

Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women

Bó

Fragoso

Farias

et al. 2023

Hematology, Transfusion and Cell Therapy

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“…The study of reticulocyte production index (RPI) could be used as a potential surrogate marker to indicate sufficient bone marrow regenerative capacity [9]. New red blood cell and reticulocyte parameters and monitoring therapy used in hemodialysis [10]. Higher reticulocyte counts were associated with higher mortality.…”

Section: Discussionmentioning

confidence: 99%

Experience of Reticulocytes Measurement at 720 nm Using Spectrophotometer

Sung

Seok

Jung³

et al. 2017

Korean J Clin Lab Sci.

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1동남보건대학교 임상병리과, 2 장원의료재단 U2Bio, 3 동수원병원 진단검사의학과, 4 분당제생병원 진단검사의학과, 5 서남대학교 의용공학과 Currently, reticulocyte experimental calculation technology used in clinical laboratories are divided two types: manual and automated. Manual reticulocyte counting using a microscopy lacks accuracy due particularly to its low reproducibility, affecting the accuracy of manual reticulocyte count. Moreover, Automatic blood corpuscle analyzer flow cytometry is difficult to be used in underdeveloped countries and small scale laboratories due to relatively high cost. Therefore, this study tried to find a new method to complement these drawbacks. The aim of this study was to compare the stained reticulocytes count by spectrophotometer and also to analyze the statistics of spectrophotometer and flow cytometer. The same 8 EDTA samples were repeated 36 times to compare the agreement between spectrophotometer and flow cytometer. This study measured the specimen diluted 600 times at 700∼780 nm by 10 differences. Wavelength between 710 to 730 by absorbance showed a positive correlation between standard data and test data (r=0.967, p＜0.01), presenting a correlation between variables. Statistical analyses of regression for test and standard parametric data, the optimal dilution factor was 600 times. Therefore, this study tried to technical utilizes such as contributing economical for the reticulocyte absorbance apply from the auto spectrophotometer, a monitoring system for the reticulocyte relation anemia, etc. Therefore, more extensive studies, including an auto chemical analyzer application, will be needed.

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“…This study also establishes other effective red cell parameters to distinguish LID from IDA or vice versa as shown in Table 2. The biochemical parameter, serum (ACD) from IDA Other research groups have also considered the utilization of various red cell parameters in characterizing hematological diseases, such as nonsickling hemoglobinopathy [26], chronic nephropathies [27], and even mortality in subjects undergoing hemodialysis [28]. In the future, simple algorithms may even be formulated by arithmetically incorporating more than one routine or eRBC parameters to achieve better distinction between 2 conditions of interest with the aid of ROC curves.…”

Section: -Specificitymentioning

confidence: 99%

Utilizing Extended Red Blood Cell Parameters to Distinguish Iron-Deficient Erythropoiesis - Related Disorders in Malaysian Female Population

Angeli¹,

Octavian²,

Yegappan³

et al. 2019

Int J Blood Res Disord

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Introduction: The full blood count (FBC) analyzers, Sysmex XE-5000 and Unicel DxH 800, are equipped to perform routine and extended parameters tests; thus, this study considered extended red blood cell (eRBC) parameters to distinguish iron-deficient erythropoiesis related disorders. Methods: Malaysian female subjects comprising three main ethnic groups (Malay, Chinese and Indian) were included. Three groups of findings were distinguished based on FBC, morphology, and iron status of the subjects: normal, latent iron deficiency (LID) and iron deficiency anemia (IDA). Spearman's correlation test was performed to assess the concordance of FBC parameters in both analyzers. Test of normality and mean comparison tests were carried out to determine statistically significant parameters (p < 0.05) in discriminating iron-deficient erythropoiesis. Finally, receiver operating characteristic (ROC) curves were generated to determine area under the curve, sensitivity, and specificity of the parameters. Results: Malaysian female subjects of the Indian ethnic group were observed to have higher prevalence of IDA (55.8%) and LID (42.7%) compared to other ethnic groups. Both analyzers were confirmed to have good correlation between RBC-Y in Sysmex XE-5000 and MAF in Unicel DxH 800

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New red blood cell and reticulocyte parameters and reference values for healthy individuals and in chronic kidney disease

Cited by 6 publications

References 16 publications

Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women

Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women

Experience of Reticulocytes Measurement at 720 nm Using Spectrophotometer

Utilizing Extended Red Blood Cell Parameters to Distinguish Iron-Deficient Erythropoiesis - Related Disorders in Malaysian Female Population

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