Solitary fibrous tumor of the larynx: report of two new cases

Girardi, Fábio Muradás; Barra, Marinez Bizarro; Girardi, Adriana Muradás

doi:10.5935/1676-2444.20140020

Jornal Brasileiro De Patologia E Medicina Laboratorial

2014

DOI: 10.5935/1676-2444.20140020

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Solitary fibrous tumor of the larynx: report of two new cases

Fábio Muradás Girardi¹,

Marinez Bizarro Barra²,

Adriana Muradás Girardi³

Abstract: Solitary fibrous tumor is a rare neoplasm. Few cases have been described in the head and neck area, and less than 11 were located in the larynx. We described two new cases of solitary fibrous tumor of the larynx. A man, 64-year-old, and a woman, 77-year-old, both with submucosal and nodular supraglottic lesions, were submitted to surgical treatment and both showed CD-34 and bcl-2 immunoreactivity and S-100 and smooth-muscle actin negativity. After 24 and 22 months of postoperative follow-up, respectively, they… Show more

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“…Only 6% of SFT develop in the head and neck and the oral cavity was reported to be the most commonly affected area. 3 Solitary fibrous tumors of the upper respiratory tract comprise <0.1% of all SFTs. 4 Cases of SFT have also been documented in the paranasal sinuses, nasopharynx and nasal cavity.…”

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Solitary Fibrous Tumor of the Larynx and Anterior Neck

Pabayos¹,

Chiong²

2019

Philipp J Otolaryngol Head Neck Surg

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Whether benign or malignant, laryngeal and neck masses may involve the upper airway and obstruct breathing. While surgically-resectable malignancies are generally extirpated with adequate margins of normal tissue, benign lesions are usually excised conservatively. However, even benign masses may behave malignantly, necessitating more aggressive surgical resection. We present one such case. CASE REPORT A 35-year-old man from Cotabato City consulted due to difficulty of breathing. He had a six-year history of progressively enlarging anterior neck mass with intermittent dyspnea, foreign body sensation, progressive dysphagia and hoarseness over the last three months. Physical examination revealed a well-defined, 5 x 6 cm smooth, firm, non-tender anterior neck mass that moved with deglutition. Rigid endoscopy showed a right supraglottic mass with bulging of the right glottic and subglottic area, with a less than 10% airway opening. (Figure 1A) Both arytenoids were visibly mobile, but glottic closure was impaired. (Figure 1B) Tracheostomy and suspension laryngoscopy with biopsy yielded inconclusive results (fibromuscular tissue) and fine needle aspiration cytology (FNAC) of the anterior neck mass only revealed blood and colloid. Contrast computed tomography of the neck showed a well-marginated, hypodense, thick-walled, heterogeneously enhancing mass in the right laryngeal fossa measuring 2.86 x 1.78 cm with a larger extension anteriorly measuring 4.66 x 2.52 cm. Effacement of the epiglottis and aryepiglottic fold was noted. The hyoid and thyroid cartilage were intact, and the thyroid gland was normal. (Figure 2A, B) Because of inconclusive histopathological and cytological results, an incision biopsy of the anterior neck mass was performed. Histopathological evaluation revealed spindle cell mesenchymal proliferation, and immunohistochemical stains showed positive immunoreactivity for CD34, with a weakly positive S-100 and negative SMA, favoring a solitary fibrous tumor.

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confidence: 99%

Solitary Fibrous Tumor of the Larynx and Anterior Neck

Pabayos¹,

Chiong²

2019

Philipp J Otolaryngol Head Neck Surg

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A rare case of Solitary Fibrous Tumor of Subglottis

Cv¹,

Hasan²,

Jacob³

et al. 2020

Arch Otolaryngol Rhinol

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Solitary fibrous tumor of the larynx: report of two new cases

Cited by 2 publications

References 11 publications

Solitary Fibrous Tumor of the Larynx and Anterior Neck

Solitary Fibrous Tumor of the Larynx and Anterior Neck

A rare case of Solitary Fibrous Tumor of Subglottis

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