Neurological dysfunction associated with COVID-19

Silva, Filipa Sofia Camacho Alves da; Bucur, Alexei; Rosado, Steeve Neves; Balhana, Sílvia; Meneses-Oliveira, Carlos

doi:10.5935/0103-507x.20210042

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2022

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“…Three potential mechanisms by which SARS-CoV-2 can affect the central nervous system (CNS) have been suggested: transsynaptic spread of the virus, dissemination through the blood–brain barrier, and immune-mediated lesions [ 1 – 3 ] . In addition, vascular involvement could result in neurological manifestations in SARS-CoV-2-associated cerebrovascular disease.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hearing Loss and Sixth Cranial Nerve Paresis after COVID-19

Villalba¹,

Pierre²,

Guerrero-Niño³

et al. 2022

European Journal of Case Reports in Internal Medicine

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An 80-year-old patient was admitted to the internal medicine department for binocular diplopia and hearing loss with sudden onset. The patient had presented with SARS-CoV-2 infection 3 weeks previously and had been admitted to hospital. Complete work-up including autoimmunity, serum and LCR viral serology and MRI did not allow a diagnosis to be established. The hypothesis of a microvascular origin or the previous SARS-CoV-2 infection was considered. The latter was retained in light of the temporal relationship, the absence of other pathologies after exhaustive work-up, and the clinical evolution.

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Section: Discussionmentioning

confidence: 99%

“…The neurological manifestations of SARS-CoV-2 have already been reported in the literature and include: meningitis, myelitis, encephalitis, CNS vasculitis, disseminated acute encephalomyelitis and post-infection acute disseminated encephalomyelitis/post-infectious brainstem encephalitis, Guillain-Barré syndrome and stroke [ 1 – 4 ] .…”

Section: Discussionmentioning

confidence: 99%