Glycerol/Hypophosphorous Acid and PhSeSePh: An Efficient and Selective System for Reactions in the Carbon-Carbon Double Bond of (E)-Chalcones

Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

“…It is well known that WR is an efficient chemoselective reduction agent for diketones [ 16 ], α,β-unsaturated thioazo and selenoazolidinones [ 6 ]. Based on the literature research and our findings, a possible mechanism for the selective reduction of N -substituted- N -phenylamidoacetophenones 4 – 6 is broadly similar to that of NaSeH and LiSeH as selective reducing agents of α,β-unsaturated carbonyl compounds [ 13 ] and of PhSe-SePh as a reducing agent for electron deficient olefins [ 25 ], and it is probable that the reduction proceed through a Micheal reaction [ 26 , 27 , 28 ].…”