Kidney transplantation in HIV positive patients. Two case reports from Hospital de Clínicas de Porto Alegre initial experience

Abstract

Recently kidney transplantation has become an accepted treatment modality for the treatment of HIV infected patients with end-stage renal diseases. For such treatment it is required stability of clinical and laboratory parameters related to HIV infection and the use of highly active antiretroviral therapy. In this report we present the first two cases in Brazil of patients with HIV infection transplanted with organs from deceased donors performed successfully in our institution. The interactions between immunosuppressive and antiretroviral drugs, the co-infections, cardiovascular risk profile and the high incidence of acute rejection remain the major problems to be dealt with in these patients.

Regional differences in the management and outcome of kidney transplantation in patients with human immunodeficiency virus infection: A 3‐year retrospective cohort study

“…involved 27 carefully selected South‐African HIV‐infected patients who received kidneys from HIV‐infected donors, and reported similar outcomes to those in non‐infected recipients over a follow‐up period of 3‐5 years . Regarding transplants from HIV‐negative donors, the only report until 2016 was made by Spuldaro et al ,. who described a successful outcome in two Brazilian recipients with well‐controlled HIV infection.…”