Study of Scott Test Using Spectroscopic Techniques: An Alternative Method for Detecting Cocaine Hydrochloride and Its Addulterants in Street Drugs

Conceição, Vitor N.; Souza, Lindamara M.; Merlo, Bianca B.; Filgueiras, Paulo R.; Poppi, Ronei J.; Romão, Wanderson

doi:10.5935/0100-4042.20140240

Cited by 6 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar results were noted with chloroform (data not shown), though the enhanced solubility of all precipitates in ethyl acetate [51] resulted in spectra with higher signal to noise. Given the color of the precipitates and their resulting solutions, peaks within the red zone of the UV-vis regions are expected.…”

Section: Blue Precipitatessupporting

confidence: 83%

Clarifying the complex chemistry of cobalt(II) thiocyanate‐based tests for cocaine using single‐crystal X‐ray diffraction and spectroscopic techniques

Burks,

Öhrström,

Amombo Noa

2023

Journal of Forensic Sciences

View full text Add to dashboard Cite

Cobalt(II) thiocyanate‐based tests are routinely used to screen cocaine products, with the formation of a blue species interpreted as a positive response. An array of other organic bases has been identified as false positives – including well‐documented cocaine product adulterant lidocaine and its salt. False positives prompt continued test development, though improvements are hindered by unresolved product structures and reaction pathways. Toward greater clarity, cobalt(II) thiocyanate reactions with cocaine hydrochloride, along with lidocaine and its salt, were investigated using multiple analytical techniques. Reactions involving cocaine hydrochloride yielded glassy, amorphous blue material while reactions of lidocaine hydrochloride monohydrate produced larger, needle‐like crystals whose structure was determined via single‐crystal X‐ray diffraction to be an ion pair (Hlidocaine+)2([Co(SCN)4]2−)·H2O. While the blue precipitate isolated from reactions involving cocaine hydrochloride was unsuitable for crystallographic structure determination, comparative ultraviolet–visible, attenuated total reflectance infrared, and Raman spectroscopic analysis – along with elemental analysis – supports that this solid is comprised of a comparable ion pair (Hcocaine+)2[Co(SCN)4]2−. Pink crystals isolated from lidocaine reaction vessels were identified as coordination compounds cis‐[CoL2(SCN)2] and trans‐[CoL2(SCN)2] where L = lidocaine, while pink crystals from both cocaine hydrochloride and lidocaine hydrochloride monohydrate reaction vessels were the coordination polymer trans‐[Co(H2O)2(SCN)2]·H2O. The results presented herein enable reaction optimization to favor a desired product, whether ion pair or coordination species.

show abstract

Section: Blue Precipitatessupporting

confidence: 83%

Clarifying the complex chemistry of cobalt(II) thiocyanate‐based tests for cocaine using single‐crystal X‐ray diffraction and spectroscopic techniques

Burks,

Öhrström,

Amombo Noa

2023

Journal of Forensic Sciences

View full text Add to dashboard Cite

show abstract

“…The axial asymmetrical deformation of the epoxide ring appears in the region of 906 cm -1 . A report in the literature [25] about the ATR-FTIR technique indicates that besides the analysis of the interaction of matter with electromagnetic radiation in the infrared range, in many cases the technique can perform quantitative analysis, since the response to the signal obtained by FTIR spectra can be related to the concentration of analyte in the sample. In the sample ACMC1:10, this band is more intense than in sample ACMC 1:5, so it is possible that the adsorption of GMA in this synthesis was more significant.…”

Section: Resultsmentioning

confidence: 99%

Core-shell magnetic particles obtained by seeded suspension polymerization of acrylic monomers

et al. 2018

View full text Add to dashboard Cite

Core-shell magnetic polymer particles were synthesized by seeded suspension polymerization. The core was made of poly(methyl methacrylate-co-divinylbenzene) and a mixture of magnetite, maghemite and goethite (P(MMA-co-DVB)-M). The shell was composed of poly(glycidyl methacrylate-co-divinylbenzene) (P(GMA-co-DVB)). These particles were characterized by infrared spectrometry (FTIR), thermal analysis (TG), scanning electron microscopy (SEM), dynamic light scattering (DLS) and vibrating sample magnetometry (VSM). The results showed the formation of core-shells with good magnetic properties (≈7.1 emu/g) and good thermal resistance (≈300 ºC). The light scattering experiments showed that the particle size of these materials changed from 5-90 microns (core) to 5-120 microns (core-shell). Scanning electron microscopic images were useful to show the formation of P(GMA-co-DVB) shells on P(MMA-co-DVB)-M cores. The materials synthesized in this work have potential to be modified and employed in magnetic separation processes in the biotech and environmental fields.

show abstract

“…The psychoactive effects initiate faster when administered by intravenous route and inhalation, compared to the oral and intranasal administration. Cocaine salts are highly diffusible in water and are thermolabile, allowing its quick absorption by the nasal mucosa [11,12].…”

Section: Discussionmentioning

confidence: 99%

Rhabdomyolysis After Cocaine Consumption-Case Report

Neto

2019

AJBSR

View full text Add to dashboard Cite

show abstract

Study of Scott Test Using Spectroscopic Techniques: An Alternative Method for Detecting Cocaine Hydrochloride and Its Addulterants in Street Drugs

Cited by 6 publications

References 0 publications

Clarifying the complex chemistry of cobalt(II) thiocyanate‐based tests for cocaine using single‐crystal X‐ray diffraction and spectroscopic techniques

Clarifying the complex chemistry of cobalt(II) thiocyanate‐based tests for cocaine using single‐crystal X‐ray diffraction and spectroscopic techniques

Core-shell magnetic particles obtained by seeded suspension polymerization of acrylic monomers

Rhabdomyolysis After Cocaine Consumption-Case Report

Contact Info

Product

Resources

About