Clinical applications of the Scheimpflug principle in Ophthalmology

Faria-Correia, Fernando; Ambrósio, Renato

doi:10.5935/0034-7280.20160035

Cited by 12 publications

(10 citation statements)

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“…Scheimpflug camera was used in the imaging of the corneas by a Pentacam device (Industria Terapeutica Splendore, Napoli, Italy) as this system has the ability to measure the dispersion of light along the optical axis, allowing the detection of changes in the transparency of the lens over time [49].…”

Section: Ophthalmologic Examinationsmentioning

confidence: 99%

Oral l-Cysteine Supplementation Enhances the Long Term-Effect of Topical Basic Fibroblast Growth Factor (bFGF) in Reducing the Corneal Haze after Photorefractive Keratectomy in Myopic Patients

et al. 2020

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We aimed at evaluating the long-term effects of l-cysteine oral supplementation to basic fibroblast growth factor (bFGF) eye-drops on corneal re-epithelization and transparency in myopic patients subjected to photorefractive keratectomy (PRK). Forty patients subjected to bilateral PRK for myopia were enrolled and randomly divided into two groups receiving an additional therapy together with the standard postoperative treatment consisting in local tobramycin 0.3%, dexamethasone 0.1%, diclofenac 0.1%, and 0.2% hyaluronate. Group 1 included 20 patients (11 males and 9 females; 34.09 ± 8 years of age) receiving only bFGF eye-drops (10 μg/10 μL) four times a day for 7 days starting from the day of surgery; Group 2 included 20 patients (12 males and 8 females; 37.35 ± 11.5 years of age) who were postoperatively administered with topical basic fibroblast growth factor (bFGF; 10 μg/10 μL) four times a day for 7 days plus oral l-cysteine supplementation (500 mg/capsule) once a day for 15 days, starting 7 days before PRK. Patients were followed-up for 12 months. Clinical ophthalmologic parameters were recorded for all the 80 examined eyes. The corneal transparency was evaluated in vivo by slit lamp and confocal microscopy. The data showed that: (a) the corneal haze occurred in a smaller percentage of the patients who were postoperatively administered with topical bFGF plus oral l-cysteine supplementation (Group 2) compared to patients who received only bFGF (Group 1); (b) at 6 months of follow-up, the stromal mean image brightness of the patients belonging to Group 2 was significantly lower than that of the Group 1 (p < 0.03), and, interestingly, the difference was even more evident at 12 month from the treatment (p < 0.001). Moreover, the final mean of the spherical equivalent refraction was −0.06 ± 0.2 D in Group 1 and −0.08 ± 0.3 D in Group 2, whereas the final uncorrected distance visual acuity (UDVA) was equal or superior to 20/25 in 100% of eyes in both Group 1 and 2. Post refractive patients can benefit from the administration of l-cysteine before the surgery and in association with bFGF in the early postoperative period, showing a faster corneal re-epithelization able to prevent corneal haze in the long-term recovery.

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Section: Ophthalmologic Examinationsmentioning

confidence: 99%

Oral l-Cysteine Supplementation Enhances the Long Term-Effect of Topical Basic Fibroblast Growth Factor (bFGF) in Reducing the Corneal Haze after Photorefractive Keratectomy in Myopic Patients

et al. 2020

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“…The Scheimpflug principle refers to a concept in geometric optics whereby a photograph of an object plane that is not parallel to the image plane can be rendered maximally focused given certain angular relations among the object plane, the lens, and the image plane (Figure 1) [2]. When applied to ophthalmic imaging, it allows for photographic documentation of the anterior segment with a depth of focus ranging from the anterior cornea to the posterior lens surface [9, 10].…”

Section: The Scheimpflug Principlementioning

confidence: 99%

“…For experienced clinicians, noncontact imaging may serve as a useful supplement to gonioscopy. It may be particularly valuable in situations where a routine examination is difficult, such as with patients who poorly tolerate gonioscopy or who have difficulty with the required positioning [1, 2, 8]. Several technologies have capabilities that may be useful in the evaluating narrow angles, which are overviewed in Table 2 [1, 3, 12].…”

Section: Anterior Chamber and Iridocorneal Angle Assessmentmentioning

confidence: 99%

“…The Pentacam (Oculus, Wetzlar, Germany) is equipped with two cameras: a rotational camera that captures the Scheimpflug image and a front camera that is used to evaluate the pupillary opening. Information obtained by the front camera aids with measurement corrections as well as the three-dimensional reconstruction (Figure 2) [2]. However, all Scheimpflug-based devices share a similar drawback when compared to UBM and ASOCT.…”

Section: Anterior Chamber and Iridocorneal Angle Assessmentmentioning

confidence: 99%

“…Scheimpflug photography is the basis for a number of devices that can image the anterior segment. The technology is highly versatile, with potential applications in the areas of keratorefractive surgery, corneal biomechanics, corneal ectasia evaluation, anterior segment imaging, cataract grading, and surgical planning for femtosecond laser-assisted cataract surgery [2–7]. …”

Section: Introductionmentioning

confidence: 99%

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Applications of Scheimpflug Imaging in Glaucoma Management: Current and Potential Applications

Nguyen

Liu

2016

Journal of Ophthalmology

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Scheimpflug photography is the basis for a variety of imaging devices that are highly versatile. The applications of Scheimpflug imaging are wide in scope, spanning from evaluation of corneal ectasia to quantifying density in nuclear sclerotic cataracts. The potential uses for Scheimpflug-based devices are expanding and a number of them are relevant in glaucoma. In particular, they can provide three-dimensional image reconstruction of the anterior segment which includes assessment of the iridocorneal angle. Photographic analyses allow also for a noncontact method of estimating central corneal thickness (CCT) and intraocular pressure (IOP), as well as the study of various corneal biomechanical properties, which may be useful for stratifying glaucoma risk.

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Screening Candidates for Refractive Surgery With Corneal Tomographic–Based Deep Learning

et al. 2020

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IMPORTANCE Evaluating corneal morphologic characteristics with corneal tomographic scans before refractive surgery is necessary to exclude patients with at-risk corneas and keratoconus. In previous studies, researchers performed screening with machine learning methods based on specific corneal parameters. To date, a deep learning algorithm has not been used in combination with corneal tomographic scans.OBJECTIVE To examine the use of a deep learning model in the screening of candidates for refractive surgery.

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Clinical applications of the Scheimpflug principle in Ophthalmology

Cited by 12 publications

References 0 publications

Oral l-Cysteine Supplementation Enhances the Long Term-Effect of Topical Basic Fibroblast Growth Factor (bFGF) in Reducing the Corneal Haze after Photorefractive Keratectomy in Myopic Patients

Oral l-Cysteine Supplementation Enhances the Long Term-Effect of Topical Basic Fibroblast Growth Factor (bFGF) in Reducing the Corneal Haze after Photorefractive Keratectomy in Myopic Patients

Applications of Scheimpflug Imaging in Glaucoma Management: Current and Potential Applications

Screening Candidates for Refractive Surgery With Corneal Tomographic–Based Deep Learning

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