Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study

Marculino, Leonardo Guedes C.; Hazarbassanov, Rossen Mihaylov; Queiroz‐Hazarbassanov, Nicolle; Hirai, Flávio E.; Filho, José Arthur Pinto Milhomens; Wakamatsu, Tais Hitomi; Gomes, José Álvaro Pereira

doi:10.5935/0004-2749.202200100

Cited by 7 publications

(6 citation statements)

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“…There are not many studies on DE in primary hypertension patients, but many studies have shown that DE is associated with hypertension in healthy people as well as in people with chronic disease. Marculino et al [17] studied the rate of DEs and the risk factors in 582 adults. The results showed that the rate of DEs accounted for 24.4%.…”

Section: Resultsmentioning

confidence: 99%

Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam

Thang,

Huynh,

Kien

et al. 2024

Int J Ophthalmol

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AIM: To determine the dry eye (DE) rate and its relationship with disease stage in patients with primary hypertension. METHODS: A cross-sectional study included 432 patients with primary hypertension (with an equal number of patients in each group: 144 in stage I, II, and III hypertension) and 144 healthy subjects as a control group. The Ocular Surface Disease Index (OSDI) and Schirmer I test without anesthetics were conducted on all 576 subjects. Subjects with OSDI scores <13 and Schirmer I values equal to or under 10 mm were diagnosed with DE. RESULTS: The ratio of DE in hypertension patients was higher than in the control group (41.7% versus 18.8%; P<0.001). The proportion of patients with DE increased gradually according to the hypertension stage: 27.1% in stage I, 40.3% in stage II, and 57.6% in stage III, P<0.001. Age, duration of hypertension, plasma urea, creatinine, and high-sensitivity C-reactive protein (CRP-hs) levels in hypertension patients with DE were higher than those without DE, P<0.001. Advanced age, a long duration of hypertension, diabetes mellitus, elevated plasma creatinine, and CRP-hs levels were independent factors associated with DE in primary hypertension patients, P<0.001. CONCLUSION: DE is a common disorder associated with advanced age, a long duration of hypertension, diabetes mellitus, elevated plasma CRP-hs, and creatinine levels in patients with primary hypertension.

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Section: Resultsmentioning

confidence: 99%

Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam

Thang,

Huynh,

Kien

et al. 2024

Int J Ophthalmol

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“…The prevalence in the population is about 5–42%. 8–10 Due to the age of patients, these values appear to be underestimated and cannot be directly related to the group of patients with cataract.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of the condition is 5–42%, according to various studies, with up to 50% of the population likely to have subjective symptoms. 8–10 The condition belongs to the spectrum of OSD. Age is one of the main risk factors for DED.…”

Section: Introductionmentioning

confidence: 99%

Dry Eye Disease as a Cause of Refractive Errors After Cataract Surgery – A Systematic Review

Biela¹,

Winiarczyk²,

Borowicz³

et al. 2023

OPTH

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Dry eye disease (DED) is a multifactorial ocular surface disorder characterized by loss of tear film homeostasis with associated ocular symptoms, like dryness, foreign body sensation, and inflammation. Numerous reports confirm an increase in dry eye symptoms after cataract surgery. DED also significantly disturbs preoperative biometric measurements, mainly by changes in keratometry measurements. The purpose of this study is to evaluate the effect of DED on biometric measurements before cataract surgery and postoperative refractive errors. PubMed database was searched for keywords: cataract surgery, dry eye disease, refractive error, refractive outcomes, keratometry, and biometry. Four clinical studies evaluating the effect of DED on refractive errors were included. In all studies, biometry was performed before and after dry eye treatment, and the mean absolute error was compared. Various substances have been used to treat dry eye, such as cyclosporin A, liftitegrast, and loteprednol. The refractive error was significantly lower after treatment in all studies. The results unanimously indicate that refractive errors can be reduced by proper treatment of DED before cataract surgery.

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“…25 The prevalence of DES increased significantly and showed a linear relationship with increasing age. 26 The prevalence of DES was said to increase by 2.0% for each decade of increasing age according to clinical diagnosis reports of dry eye and 10.5% based on the Schimer test. 4 At the age of over 40 years the main cause of DES is Meibomian Gland Dysfunction (MGD).…”

Section: Discussionmentioning

confidence: 99%

Kadar Vitamin D dengan Sindrom Mata Kering pada Karyawan

Margo,

Meiyanti,

Kartadinata

et al. 2023

J Biomedika dan Kesehat

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Latar Belakang Sindrom mata kering (DES) penyakit mata yang paling sering dijumpai dengan prevalensi di dunia sekitar 5 – 50%. Di Indonesia sendiri prevalensi DES sekitar 27.5%. DES disebabkan oleh banyak faktor yang menunjukkan inflamasi memegang peranan penting dalam patofisiologinya. Akibat adanya inflamasi akan menyebabkan peningkatan stress oksidatif yang dapat menyebabkan penurunan produksi air mata, dan inflamasi pada permukaan okuler dapat menyebabkan peningkatan penguapan air mata yang berlebihan sehingga menyebabkan ketidakstabilan lapisan air mata. Vitamin D mempunyai efek anti inflamasi. Peranan vitamin D pada mata melalui vitamin D reseptor (VDR) yang terekspresi pada epitel pigmen retina, fotoreseptor retina, lapisan sel ganglion, korpus siliaris, lensa, epitel dan endotel kornea, serta aquous humor, vitreous humor dan lapisan air mata. Defisiensi vitamin D dikatakan mempunyai kontribusi dalam DES, namun ada penelitian lain menyatakan tidak ada hubungan kadar vitamin D serum dengan DES. Atas dasar hal tersebut, maka tujuan penelitian ini untuk meneliti hubungan kadar vitamin D dengan DES. Metode Penelitian ini merupakan penelitian observasional analitik dengan design crosssectional yang diikuti oleh karyawan FK USAKTI yang dilakukan pada bulan Februari – Maret 2021. Sebanyak 57 subjek berusia 25-60 tahun sesuai kriteria dan bersedia mengikuti penelitian ini. Pemeriksaan DES dilakukan dengan kuesioner OSDI, tes Schimer dan tear break-up time (TBUT). Pemeriksaan vitamin D dengan cara mengukur kadar 25(OH)D. Analisis dengan uji chi-square dengan tingkat kemaknaan yang digunakan p < 0.05. Hasil Pada pemeriksaan kadar vitamin D dengan penderita DES dengan tes Schimer ditemukan tidak berhubungan (p=0.948), dibandingkan pemeriksaan kadar vitamin D dengan TBUT ditemukan berhubungan bermakna (p=0.030), sedangkan dengan menggunakan kuesioner OSDI ditemukan tidak berhubungan (p=0.285). Kesimpulan Terdapat hubungan bermakna antara kadar vitamin D dengan DES melalui pemeriksaan TBUT.

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Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study

Cited by 7 publications

References 0 publications

Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam

Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam

Dry Eye Disease as a Cause of Refractive Errors After Cataract Surgery – A Systematic Review

Kadar Vitamin D dengan Sindrom Mata Kering pada Karyawan

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