Fibrofoliculoma solitário: revisão de série retrospectiva de casos de 18 anos

Abstract

The purpose of this study was to report a series of cases of solitary fibrofolliculoma, a lesion seldom observed in the lids. Demographics, as well as clinical and histological aspects of the lesion were evaluated. Methods: This was a retrospective case series spanning a period of 18 years. All the included patients were diagnosed with solitary fibrofolliculoma confirmed by histological examination. Data regarding patient demographics, signs, and symptoms, course of the disease, location of the lesion, clinical and histological diagnosis, and outcome were collected. Results: Eleven cases of solitary fibrofolliculoma were diagnosed in the study period. The median age of patients was 51 ± 16.3 years (range: 27-78 years). Most patients were females (7/11; 64%). Five of the patients (45%) were asymptomatic; four (36%) reported bleeding, one (9%) had referred itching, and one (9%) rubbing of the lesion. The lesion occurred in a wide range of locations; one of them was located in the lids. The diagnosis for all lesions was histological based on characteristic findings of a hair follicle occasionally dilated and containing keratin material surrounded by a moderately well-circumscribed thick mantle of fibrous tissue. The infundibular follicular epithelium extended out into this fibrous mantle forming epithelial strands or cords. There were no relapses after exeresis. Conclusion: Solitary fibrofolliculoma is a rare lesion, seldom affecting the eyelids. We reported 11 cases, and the third case reported thus far in the literature affecting the lids. Diagnosis may be easily missed due to the nonspecific symptoms and clinical appearance.Therefore, it is necessary to perform excisional biopsy and histological examination for the recognition of this lesion.

A Solitary Fibrofolliculoma in Close Proximity to the Medial Canthus

“…In contrast to multiple fibrofolliculomas, a solitary lesion by itself does not have a genetic predisposition and is not associated with other cutaneous abnormalities [3]. There are only four previous cases in the literature of a solitary fibrofolliculoma described on the eyelid [4][5][6][7]. Here, we report the first case (to our knowledge) of a solitary fibrofolliculoma located in close proximity to the medial canthus in an otherwise healthy 43-yearold female.…”