“…3,14,21,22 Evidence has shown us that the impact of such a stance in the case of IKE, in which the source of infection is contiguous to the intraocular space, leads to significantly different functional and anatomical outcomes from those reported by the EVS, with a high prevalence of NLP and a huge proportion of patients requiring enucleation/evisceration surgery to achieve the control of the infection. 14,23,24 Moreover, the presence of severe corneal pathologies, such as corneal infiltration, ulcers, or opacities, hinders the correct assessment of visual acuity at the moment of diagnosis. 24 Therefore, trying to select the appropriate moment to institute surgical therapy based solely on visual acuity may be difficult and misleading.…”