Descemet’s membrane endothelial keratoplasty for acute corneal hydrops: a case report

Maranhão, Lucio V L; Ramalho, Natália Regnis L; Pinto, Wanessa M P; Dantas, Paulo E.C.; Ventura, Camila V.

doi:10.5935/0004-2749.20200085

Cited by 1 publication

(1 citation statement)

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“…As early as 1988, Zusman et al [13] proposed that intracameral sulfur hexafluoride (SF 6 ) injection could repair DM detachment. Afterwards, various kinds of agents like air [14][15] , SF 6 [16] , perfluoropropane (C 3 F 8 ) [17][18] , sodium hyaluronate [19] , intrastromal fluid drainage with air tamponade [20] , tissue glue [21] , intracameral platelet-rich plasma injection [22] , and descemet membrane endothelial keratoplasty (DMEK) [23][24] have been proven effective in treating acute corneal hydrops. Among these techniques, intracameral air/gas injection has been widely proven for the acceleration of the resolution of corneal oedema [25][26] .…”

Section: Discussionmentioning

confidence: 99%

Different compression sutures combined with intracameral air injection for acute corneal hydrops

Liu¹,

Qu²,

Qiao³

et al. 2022

Int J Ophthalmol

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AIM: To evaluate the efficacy and safety of full-thickness sutures combined with intracameral air injection (FTS-AI) versus pre-Descemet’s membrane sutures combined with intracameral air injection (PDS-AI) in the management of acute corneal hydrops in keratoconus. METHODS: The research included 8 patients (8 eyes) suffering from acute corneal hydrops caused by keratoconus. Four patients were randomly assigned to FTS-AI. And the other four were randomly assigned to PDS-AI. Corneal oedema, visual acuity, corneal thickness were assessed during follow-up. RESULTS: The demographics, preoperative duration of symptoms and severity of corneal hydrops between the two groups were not significantly different. The mean corneal oedema resolution time after FTS-AI and PDS-AI were 11±1.15 and 15±1.41d, respectively (P=0.005). The maximum corneal thickness of the scarred region decreased in both groups at one week postoperatively (P<0.05). No obvious difference was found in the mean maximal corneal thickness between the two groups postoperatively. The BCVA improved significantly after FTS-AI and PDS-AI at three months postoperatively. No obvious difference was found in the BCVA after FTS-AI and PDS-AI at three months postoperatively. CONCLUSION: FTS-AI and PDS-AI are safe and effective therapies to accelerate the resolution of corneal oedema in acute corneal hydrops secondary to keratoconus. Despite faster resolution of corneal oedema in the FTS-AI group, we recommend PDS-AI to avoid potential endothelium cell damage.

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