Effects of axial length on retinal nerve fiber layer and macular ganglion
            cell-inner plexiform layer measured by spectral-domain OCT

Francisconi, Carolina Lampert Monte; Wagner, Mário Bernardes; Ribeiro, Roberto Vanin Pinto; Freitas, André Moraes

doi:10.5935/0004-2749.20200039

Cited by 15 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been reported that magnification correction affects the cpRNFL thickness, and that the cpRNFL thickness is negatively correlated to the axial length without magnification correction; however, it has shown no correlation or positive correlation to the axial length with magnification correction. [4][5][6][7][8] Similar findings were also observed using macular GCL imaging. 5,9 The recent development of OCT-based angiography (OCT-A) has enabled the assessment of vascular perfusion and its quantification with indices such as microvascular density.…”

Section: Introductionmentioning

confidence: 53%

“…[4][5][6][7][8] Similar findings were also observed using macular GCL imaging. 5,9 The recent development of OCT-based angiography (OCT-A) has enabled the assessment of vascular perfusion and its quantification with indices such as microvascular density. 10 Additionally, OCT-A detects structural changes with early glaucoma.…”

Section: Introductionmentioning

confidence: 53%

“…This trend was similar to the relationship between the axial length and cpRNFL thickness with and without magnification correction. 5,7 Hirasawa et al 24 reported an association between the different circle diameters and cpRNFL thickness and a linear relationship between the circle diameters of 2.8 mm and 4.0 mm. If this result can also be applied to the cpVD, then magnification correction will be important to achieving accurate cpVD measurements.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Structure–Function Relationships and Glaucoma Detection with Magnification Correction of OCT Angiography

Hirasawa

Yamaguchi

Nagano

et al. 2022

Ophthalmology Science

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

Section: Introductionmentioning

confidence: 53%

Section: Introductionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Structure–Function Relationships and Glaucoma Detection with Magnification Correction of OCT Angiography

Hirasawa

Yamaguchi

Nagano

et al. 2022

Ophthalmology Science

View full text Add to dashboard Cite

show abstract

“…Most studies did not adjust this magnification. As demonstrated previously, after adjusting magnification, global and nontemporal RNFL measurements were negatively associated with AL [ 53 ], while global RNFL thickness became thicker in axial myopia [ 54 ]. Due to the considerable impact of the ocular magnification effect on the peripapillary RNFL measurements, routine correction for this factor using Littmann's formula, described by Bennett et al [ 55 ], should be considered.…”

Section: Axial Length (Al)mentioning

confidence: 63%

Factors Associated with Changes in Peripapillary Retinal Nerve Fibre Layer Thickness in Healthy Myopic Eyes

Xue

et al. 2021

Journal of Ophthalmology

View full text Add to dashboard Cite

Myopic people face an elevated risk of primary open angle glaucoma. Changes in the fundus in people with high myopia often lead to misdiagnosis of glaucoma, as this condition has many clinical signs in common with myopia, making the diagnosis of glaucoma more challenging. Compared to reduction of the visual field, a decrease in retinal nerve fibre layer (RNFL) thickness occurs earlier in glaucoma, which is widely considered useful for distinguishing between these conditions. With the development of optical coherence tomography (OCT), RNFL thickness can be measured with good reproducibility. According to previous studies, this variable is not only affected by axial length but also related to the patient’s age, gender, ethnicity, optic disc area, and retinal blood flow in myopia. Herein, we intend to summarize the factors relevant to the RNFL in myopia to reduce the false-positive rate of glaucoma diagnosis and facilitate early prevention of myopia.

show abstract

“…Thus, increasing AL can correlate with inner retinal thinning. 5 , 76 , 77 It has been reported that as aging progresses, inner retinal thinning and thickening of OPL with or without interdigitation zone occurs in humans. 78 Additionally, the thickness of inner retinal sublayers is reported to reflect the inner retinal functions of many ocular and systemic diseases.…”

Section: Discussionmentioning

confidence: 99%

Normative Data of Axial Length, Retinal Thickness Measurements, Visual Evoked Potentials, and Full-Field Electroretinography in Female, Wild-Type Minipigs

Choi

Anh

et al. 2021

Trans. Vis. Sci. Tech.

View full text Add to dashboard Cite

Purpose The purpose of this study was to present normative data of optical coherence tomography (OCT), electrophysiological, and ocular biometry parameters and their correlation in minipigs. Methods Eighty-eight eyes of 44 minipigs underwent full-field electroretinogram (ERG) recording and ocular biometry. However, 10 eyes of 6 minipigs were excluded because of poor OCT image quality. The thickness of the retinal sublayers was measured on a vertical line at 5 locations with a 1 mm interval from the disc margin to the dorsal periphery and at 10 locations on the visual streak. Visual evoked potentials (VEPs) were measured in 15 eyes of 8 minipigs. Results All minipigs were female with a mean age and axial length of 13.83 ± 10.56 months and 20.33 ± 0.88 mm, respectively. The implicit time of the a-wave and b-wave in scotopic 3.0 ERGs was longer than that in photopic 3.0 ERG. The implicit time of the n2-wave and p2-wave in VEP was 25.67 ± 7.41 ms and 52.96 ± 10.38 ms, respectively. The total retinal layer (TRL) and nerve fiber layer (NFL) became thinner near the periphery. The inner retinal sublayers near the visual streak were thicker than those at other locations. Central TRL and NFL thickness on visual streak was 223.06 ± 23.19 µm and 74.03 ± 13.93 µm, respectively. The temporal TRL and NFL on the visual streak were thicker than those on the nasal side. Conclusions The normative electrophysiological and OCT parameters used in our study can be used as reference data in further pig studies. Translational Relevance This study presents normative data of minipigs, which are adequate animal models for preclinical studies.

show abstract

Effects of axial length on retinal nerve fiber layer and macular ganglion cell-inner plexiform layer measured by spectral-domain OCT

Cited by 15 publications

References 0 publications

Structure–Function Relationships and Glaucoma Detection with Magnification Correction of OCT Angiography

Structure–Function Relationships and Glaucoma Detection with Magnification Correction of OCT Angiography

Factors Associated with Changes in Peripapillary Retinal Nerve Fibre Layer Thickness in Healthy Myopic Eyes

Normative Data of Axial Length, Retinal Thickness Measurements, Visual Evoked Potentials, and Full-Field Electroretinography in Female, Wild-Type Minipigs

Contact Info

Product

Resources

About