Algorithm for dry eye disease diagnosis in individuals infected with human T-cell lymphotropic virus type 1

Castro-Lima-Vargens, Cristina; Grassi, Maria Fernanda Rios; Boa-Sorte, Ney; Rathsam-Pinheiro, Regina Helena; Almeida, Paula Caroline Matos; Galvão–Castro, Bernardo

doi:10.5935/0004-2749.20170090

Cited by 3 publications

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“…when abnormal results from all three tests were obtained, which could have led to an underestimation of the actual prevalence rate. 33 In Japan, KCS is usually associated with Sjögren's syndrome, and the reported prevalence of HTLV-1 in patients with KCS was 15.4% in 1991. 14 , 34 Unfortunately, due to the approach employed, these author's results were not suitable for inclusion in our comparison due to the reversed HTLV-1/KCS association.…”

Section: Discussionmentioning

confidence: 99%

Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load

Rathsam-Pinheiro

Boa‐Sorte

Grassi

et al. 2019

The Brazilian Journal of Infectious Diseases

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Section: Discussionmentioning

confidence: 99%

Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load

Rathsam-Pinheiro

Boa‐Sorte

Grassi

et al. 2019

The Brazilian Journal of Infectious Diseases

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“…However, if the OSDI and/or TBUT results are abnormal, a Schirmer I test is performed, with positivity confirming KCS diagnosis. Lastly, in patients with an indeterminate diagnosis (i.e., negative Schirmer I test), Rose Bengal staining must then be performed ( 63 ). Unexpectedly, uveitis was diagnosed in only 2.8% of the patients seen at CHTLV ( 64 ).…”

Section: Profile Of People Living With Human T-cell Lymphotropic Viru...mentioning

confidence: 99%

Integrative and Multidisciplinary Care for People Living With Human T-Cell Lymphotropic Virus in Bahia, Brazil: 20 Years of Experience

et al. 2022

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Brazil is home to the highest absolute number of human T-cell lymphotropic virus type-1 (HTLV-1)-infected individuals worldwide; the city of Salvador, Bahia, has the highest prevalence of HTLV-1 infection in Brazil. Due to the complex nature of several diseases associated with this retrovirus, a multidisciplinary health care approach is necessary to care for people living with HTLV-1. The Bahia School of Medicine and Public Health’s Integrative Multidisciplinary HTLV Center (CHTLV) has been providing support to people living with HTLV and their families since 2002, striving to ensure physical and mental well-being by addressing biopsychosocial aspects, providing clinical care and follow-up, including to pregnant/postpartum women, as well as comprehensive laboratory diagnostics, psychological therapy, and counseling to family members. To date, CHTLV has served a total of 2,169 HTLV-infected patients. The average patient age is 49.8 (SD 15.9) years, 70.3% are female, most are considered low-income and have low levels of education. The majority (98.9%) are HTLV-1 cases, and approximately 10% have been diagnosed with tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM), while 2.2% have infective dermatitis and 1.1% have adult T-cell lymphoma. In all, 178 pregnant/postpartum women [mean age: 32.7 (±6.5) years] have received care at CHTLV. Regarding vertical transmission, 53% of breastfed infants screened for HTLV tested positive in their second year of life, nearly 18 times the rate found in non-breastfed infants. This article documents 20 years of experience in implementing an integrative and multidisciplinary care center for people living with HTLV in Bahia, Brazil. Still, significant challenges remain regarding infection control, and HTLV-infected individuals continue to struggle with the obtainment of equitable and efficient healthcare.

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Dry eye disease caused by viral infection: Past, present and future

Wu,

Sun,

Shi

et al. 2023

Virulence

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Algorithm for dry eye disease diagnosis in individuals infected with human T-cell lymphotropic virus type 1

Abstract: This study shows the need to use multiple tests to evaluate tear film quality and include a symptom questionnaire as part of the diagnostic algorithm for dry eye disease.

Cited by 3 publications

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Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load

Revisiting Keratoconjunctivitis sicca associated with Human T-Cell Lymphotropic Virus Type 1: prevalence, clinical aspects and proviral load

Integrative and Multidisciplinary Care for People Living With Human T-Cell Lymphotropic Virus in Bahia, Brazil: 20 Years of Experience

Dry eye disease caused by viral infection: Past, present and future

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