Ocular sarcoidosis masked by positive IgM for toxoplasmosis

Peres, Murilo Bertazzo; Sousa, Jacqueline Martins de; Nascimento, Heloísa

doi:10.5935/0004-2749.20170030

Cited by 2 publications

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“…It was detected in >90% patients with biopsy-proven sarcoid uveitis in one study [5]. Typical clinical presentations in patients with anterior chamber inflammation can include pain, erythema, and worsening vision [6].…”

Section: Discussionmentioning

confidence: 98%

A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor

Wesolow¹,

Ramsakal²

2019

Int J Case Rep Images

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Introduction: Sarcoidosis is often an overlooked differential diagnosis in many disease processes. It is a nonspecific inflammatory disease marked by granulomas. Being nonspecific makes it a more difficult disease to diagnose. It is a challenging diagnosis as it is a great mimicker of many other conditions and therefore missed. The finding of a granuloma is not specific for sarcoidosis as other disorders may present with granulomas. It is an important differential to keep in mind because of significant morbidity and mortality associated with this disease. Case Report: Here we present a case of a female patient with vision loss and an intracranial mass. The mass was initially thought to be cancer and hence referred to our Cancer Center for further evaluation and workup. Upon biopsy the mass was diagnosed as sarcoidosis. She had no other systemic involvement at time of diagnosis. What makes this case of sarcoidosis rare is her solitary optic nerve involvement. Conclusion: Sarcoidosis is a more difficult disease to diagnose than other diseases, such as coronary artery disease, hyperlipidemia, and diabetes as these diseases have very specific, easily accessible

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Section: Discussionmentioning

confidence: 98%

A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor

Wesolow¹,

Ramsakal²

2019

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Heerfordt-Waldenström Syndrome, A Rare Presentation of Sarcoidosis in a Patient with Old Ocular Toxoplasmosis

Mobini

Amiri

Ghasemian

et al. 2021

IDDT

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Background: There are similarities between ophthalmic presentation of toxoplasmosis and sarcoidosis and there are some concerns of immunosuppressive treatments for sarcoidosis may lead to T. gondii reactivation. We report a rare case with acute sarcoidosis (Heerfordt-Waldenström syndrome) and past history of ocular toxoplasmosis from the North of Iran. Case presentation: The patient was a 36-year-old woman, with left painful eye and swollen parotid, right facial paresis, maculopapular rash in left eyebrow and erythema nodosa on both legs. Anti–Toxoplasma IgG antibody was positive and IgM was not detectable. Radiographic findings on chest revealed bilateral hilar lymphadenopathy. The initial treatment was sulfamethoxazole-trimethoprim to prevent recurrence of retinal toxoplasmosis and corticosteroid and mycophenolate mofetil for sarcoidosis. The patient showed clinical and vision improvement without recurrences during three months follow-up. Discussion: Ophthalmological examinations and laboratory test to rule out toxoplasmosis could be considered in known cases of sarcoidosis particularly in ocular sarcoidosis status. To the best of our knowledge this is first report of co-morbidity of ocular toxoplasmosis / sarcoidosis from Iran and possibly the world.

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Ocular sarcoidosis masked by positive IgM for toxoplasmosis

Cited by 2 publications

References 0 publications

A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor

A rare case of solitary optic nerve sarcoidosis mimicking an ocular tumor

Heerfordt-Waldenström Syndrome, A Rare Presentation of Sarcoidosis in a Patient with Old Ocular Toxoplasmosis

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