An uncommon ocular manifestation of Sweet syndrome: peripheral ulcerative keratitis and nodular scleritis

Bilgin, Ahmet Burak; Tavas, Pınar; Türkoğlu, Elif Betül; İlhan, Hatice Deniz; Toru, Havva Serap; Apaydin, Kadri Cemil

doi:10.5935/0004-2749.20150015

Cited by 7 publications

(11 citation statements)

References 8 publications

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“…The diagnosis of Sweet syndrome is based on two major and two of four minor criteria's (Table 1) [13,14,15]. Our patient met almost all of the major and minor criteria required for the diagnosis of Sweet syndrome.…”

Section: Discussion:-mentioning

confidence: 81%

Sweet Syndrome in a Patient With Systemic Lupus Erythematosus Flare.

Siddiqui¹,

Brown²,

Haghshenas³

et al. 2016

IJAR

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Section: Discussion:-mentioning

confidence: 81%

Sweet Syndrome in a Patient With Systemic Lupus Erythematosus Flare.

Siddiqui¹,

Brown²,

Haghshenas³

et al. 2016

IJAR

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“…In our patient, one of the differential diagnoses was granulomatosis with polyangiitis (GPA). Lung disease develops in most individuals with GPA, varying from asymptomatic lung nodules to fulminant alveolar hemorrhage, and cutaneous PG‐like ulcerations and nodular scleritis (NS) have been reported in several individuals . GPA, but not PG, is characterized by necrotizing granulomatous vasculitis and the presence of cytoplasmic antineutrophil cytoplasmic antibodies, which were negative in our patient.…”

Section: Discussionmentioning

confidence: 89%

“…To the best of our knowledge, NS has been reported in only three adults with PG . The most frequent systemic diseases associated with NS are rheumatoid arthritis and GPA, although other neutrophilic dermatoses such as Behçet and Sweet syndromes have also been reported . The patient had no other clinical findings to support the diagnoses of Behçet or Sweet syndrome.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary nodules and nodular scleritis in a teenager with superficial granulomatous pyoderma gangrenosum

Contreras-Verduzco

Espinosa‐Padilla²,

Orozco‐Covarrubias³

et al. 2017

Pediatric Dermatology

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Superficial granulomatous pyoderma gangrenosum, a rare variant of pyoderma gangrenosum, has been considered to be the most benign form of the disease. We present the case of a 15-year-old boy with pulmonary involvement and nodular scleritis associated with this unusual type of pyoderma gangrenosum and discuss its differential diagnosis. | CASE REPORTA 15-year-old boy presented with a pustular, warty eruption of 4 months duration. Cutaneous lesions involving the scalp, trunk, limbs, and genitals were characterized by numerous pustules surrounded by an erythematous halo and vegetative and keratotic plaques with crusts and purulent discharge overlying ulcerated, slightly painful plaques ( Figure 1A,B). Ocular examination showed erythema, conjunctival injection, and scleral nodules (Figure 2A). Several 2-to 3-mm pustules were seen on the hard palate. He also had marked digital clubbing and cyanosis ( Figure 2B), despite pulmonary auscultation with no remarkable findings, absence of dyspnea, and pulse oximetry of 92%.The patient's disease had started 9 months before with cough and he was treated for chronic bronchitis, with partial improvement.Five months before the onset of the dermatosis, he was empirically treated for pulmonary tuberculosis, but the cough persisted.During examination, a pathergy test was negative, and chest Xrays revealed a reticulonodular pattern and probable bronchiectases.Computed tomography (CT) showed pleural fibrosis, the vascular pattern was more apparent, and noncavitated nodules. Paranasal sinus CT was normal. Lung function tests showed a mild restrictive pattern. Bronchoscopy revealed mild tracheoendobronchitis with a diffuse nodular pattern. Tests were negative for microorganisms. Pulmonary hypertension was excluded. Complete blood cell count showed leukocytosis (12 9 10 3 /mm) with neutrophilia (77%). Erythrocyte sedimentation rate (22 mm/h) and C-reactive protein

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“…The most important clinical clue is a decrease in visual acuity. Inflammation of anterior structures may also cause patients to complain of blurry vision . Hence, any visual impairment in Sweet syndrome should promptly be referred to an ophthalmologist to prevent ocular morbidity.…”

Section: Discussionmentioning

confidence: 99%