Analysis of immediate transfusion incidents reported in a regional blood bank

Abstract

BackgroundBlood transfusion is imperative when treating certain patients; however, it is not risk free. In addition to the possible transmission of contagious infectious diseases, incidents can occur immediately after transfusion and at a later time.AimsThis study aimed to examine the immediate transfusion incidents reported in a regional blood bank in the state of Minas Gerais between December 2006 and December 2009. A retrospective quantitative epidemiological study was conducted. Data were obtained from 202 transfusion incident reports of 42 health institutions served by the blood bank. Data processing and analysis were carried out using the Statistical Package for the Social Sciences (SPSS) software.ResultsThe rate of immediate transfusion incidents reported in the period was 0.24%; febrile non-hemolytic reactions were the most common type of incident (56.4%). The most frequent clinical manifestations listed in transfusion incident reports were chills (26.9%) and fever (21.6%). There was a statistically significant association (p-value < 0.05) between the infusion of platelet concentrates and febrile non-hemolytic reactions and between fresh frozen plasma and febrile non-hemolytic reaction. The majority (73.3%) of transfused patients who suffered immediate transfusion incidents had already been transfused and 36.5% of the cases had previous transfusion incident reports.ConclusionsData from the present study corroborate the implementation of new professional training programs aimed at blood transfusion surveillance. These measures should emphasize prevention, identification and reporting of immediate transfusion incidents aiming to increase blood transfusion quality and safety.

Hemovigilância: a experiência da notificação de reações transfusionais em Hospital Universitário

“…These findings are confirmed by both the national literature, which indicates FNHTR (1,6,8) as the most reported reaction in NOTIVISA by hospitals of the Sentinel Network, as well as the international literature, which suggests a higher incidence of FNHTR reactions, followed by allergic reactions (12,16,(18)(19)(20)(21) . When data from NOTIVISA recorded between 2007 and 2015 are analyzed separately, we see that FNHTR and allergic reactions are more prevalent in SNH, with incidence rates of 49% and 37.3%, respectively (6) .…”

Acute blood transfusion reactions in a tertiary care hospital in Pakistan ‐ an initiative towards haemovigilance

“…Blood transfusion is an indispensable component of patient management. However, blood transfusion therapy may cause acute or delayed transfusion reactions (Sousa Neto & Barbosa, ). A transfusion reaction is defined as any transfusion‐related adverse event that occurs during or after the transfusion of blood or its components (Rathod et al ., ).…”

“…A transfusion reaction is defined as any transfusion‐related adverse event that occurs during or after the transfusion of blood or its components (Rathod et al ., ). Acute transfusion reactions (ATRs) occur during or within 24 h of transfusion and include acute haemolytic transfusion reaction (AHTR), allergic, febrile non‐haemolytic transfusion reaction (FNHTR), fluid overload, transfusion‐related acute lung injury (TRALI), anaphylactic and metabolic reactions (Khalid et al ., ; Sousa Neto & Barbosa, ).…”

Transfusion reaction and hemovigilance: An imperative discussion in Brazilian hemotherapy services

“…The main goal in developing hemovigilance programs is to increase the number of notifications of transfusion adverse events [9][10][11][12].…”