Synthesis of coumarin derivative using polymer supported reagents

Mhiri, C.; Ternane, Riadh; Hamdi, Naceur; Baklouti, Lassaad

doi:10.5155/eurjchem.9.2.89-91.1691

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…This synthetic strategy has seen some applications in the production of natural scaffolds too. In 2018, Mhiri and co-workers proposed a synthetic pathway for coumarin derivatives involving polymer supported reagents [290]. In the mentioned study, coumarin derivative A was prepared from 3-metoxy salicylaldheyde using reagents supported in a macroporous ion exchange resin, through the hydrolysis of the two intermediates iminocoumarin B and unsaturated nitrile C (Scheme 2).…”

Section: Flow Chemistry and Immobilized Reagentsmentioning

confidence: 99%

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

Annunziata

Pinna

Dallavalle

et al. 2020

IJMS

251

156

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Privileged structures have been widely used as an effective template for the research and discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and it can be found in a considerable number of plants as well as in some fungi and bacteria. In the last years, these natural compounds have been gaining an increasing attention from the scientific community for their wide range of biological activities, mainly due to their ability to interact with diverse enzymes and receptors in living organisms. In addition, coumarin nucleus has proved to be easily synthetized and decorated, giving the possibility of designing new coumarin-based compounds and investigating their potential in the treatment of various diseases. The versatility of coumarin scaffold finds applications not only in medicinal chemistry but also in the agrochemical field as well as in the cosmetic and fragrances industry. This review is intended to be a critical overview on coumarins, comprehensive of natural sources, metabolites, biological evaluations and synthetic approaches.

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Section: Flow Chemistry and Immobilized Reagentsmentioning

confidence: 99%

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

Annunziata

Pinna

Dallavalle

et al. 2020

IJMS

251

156

View full text Add to dashboard Cite

show abstract

“…At the same time, even a new perspective to the coumarin and polymers involves the synthesis of coumarin derivatives using polymer-supported reagents as an effective way for better isolation and purification [82].…”

Section: Coumarins Into Polymersmentioning

confidence: 99%

Coumarins into Polyurethanes for Smart and Functional Materials

et al. 2020

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Polyurethanes are of undoubted interest for the scientific community and the industry. Their outstanding versatility from tailor-made structures turns them into major polymers for use in a wide range of different applications. As with other polymers, new, emerging molecules and monomers with specific attributes can provide new functions and capabilities to polyurethanes. Natural and synthetic coumarin and its derivatives are characterised by interesting biological, photophysical and photochemical properties. Then, the polyurethanes can exploit those features of many coumarins which are present in their composition to achieve new functions and performances. This article reviews the developments in the proper use of the special properties of coumarins in polyurethanes to produce functional and smart materials that can be suitable for new specific applications.

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Synthesis of coumarin derivative using polymer supported reagents

Cited by 2 publications

References 11 publications

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities

Coumarins into Polyurethanes for Smart and Functional Materials

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