Synthesis of some new pyrazolylfuropyrimidinethiones and triazolofuropyrimidinethiones

Synthesis, Characterization, and Antimicrobial Evaluation of the Novel Triazolotriazolopyridines and Pyridotriazolotriazines

“…4-Aryl-1,6-diamino-2-oxo-1,2-dihydropyridine-3,5dicarbonitriles have been used for the synthesis of biologically active nitrogen bridgehead triazolo [1,5-a]pyridines [1][2][3], pyrido [1,2-b] [1,2,4]triazines [4,5], and pyrido [1,2-b] [1,2,4]triazepines [6,7]. As a part of our previously mentioned work directed for the synthesis of new polynuclear bioactive heterocyclic systems [8][9][10][11][12][13][14][15][16], the present work aimed to synthesize and utilize the novel 2-hydrazinyl-7-(4-methoxyphenyl)-5-oxo-3,5-dihydro [1,2,4]triazolo [1,5-a] pyridine-6,8-dicarbonitrile (5) as a precursor to synthesize a novel series of polyfused heterocyclic systems including [1,2,4] [1,2,4]triazines and evaluate their antimicrobial activity.…”