Synthesis, antimicrobial activity and absorption studies of some novel heterocyclic dyes based on 4-hexylbenzene-1,3-diol

Abstract

KEYWORDSAniline derivatives were diazotized and coupled with 3-aminocrotononitrile to give the corresponding 2-arylhydrazono-3-ketiminobutyronitriles. Cyclization of these arylhydrazono derivatives with hydrazine monohydrate afforded 5-amino-4-arylazo-3-methyl-1H-pyrazoles which were subsequently diazotized and coupled with malononitrile to yield a series of pyrazolylhydrazonomalononitriles. These compounds were then reacted with hydrazine monohydrate to provide, heterocyclic dyes, which were further diazotized and coupled with 4-hexylbenzene-1,3-diol to produce novel heterocyclic tetraazo dyes which were characterized by elemental analysis and spectral methods. The antimicrobial activity and absorption characteristics of the dyes were also examined in detail.Pyrazole Solvatochromism Heterocyclic dyes Antimicrobial activity 3-Aminocrotononitrile 4-Hexylbenzene-1,3-diol

Design, synthesis and biological evaluation of new Mannich products using ethyl ammonium nitrate as reusable ionic liquid

“…The antimicrobial activity of the synthesized compounds has been evaluated by filter paper disc method [36][37][38][39][40][41]. The synthesized compounds have been tested for their antibacterial activity against E. coli MTCC 443, P. Aeruginosa MTCC 1688, S. Aureus MTCC 96, and S. Pyogenus MTCC 442 and antifungal activity against Candida albicans MTCC 227, Aspergillus niger, MTCC 282 and A. Clavatus MTCC 1323 at a concentration of 500 g/mL in DMF.…”

Synthesis and evaluation of novel antibacterial monoazo disperse dyes based on sulfonamide derivatives on polyester

“…The azo dyes constitute the largest chemical class, containing at least 66 per cent of all colourants (Zollinger, 1987). It has been found that antibacterial properties of some azo dyes are due to the presence of active functional groups (Yousefi et al , 2012; Patel, 2012; Shridhar et al , 2012; Kadi, 2011; Karcı et al , 2009; Sayed and El-Gaby, 2001).…”