“…The 1,2,4-triazolopyrimidines have also attracted growing interest due to their important pharmacological activities, such as antitumor potency, antimalarial, antimicrobial, anti-inflammatory, antifungal and macrophage activation [37,38,39,40,41,42]. In continuation of our ongoing work [43,44,45,46,47,48], we report herein the synthesis of some new thiadiazole, thiazole and pyrido[2,3- d ][1,2,4]triazolo[4,3- a ]pyrimidine derivatives containing 1,2,3-triazole moieties.…”