Non-traumatic myositis ossificans

Aggressive atraumatic myositis ossificans in a toddler

“…In the presence of concerning signs, possibly indicating a more worrisome diagnosis, a biopsy could be warranted. For the tissue biopsy the sampling should involve an area from the center to the periphery to demonstrate the “zonal pattern,” obtaining tissue solely from the center risks obscuring the diagnosis even more [5 , 26] .…”

“…In most cases MO is a self-limited process with complete resolution, however, the genetic forms and aggressive or resistant cases can present a therapeutic challenge [14 , 15] . For uncomplicated MO, the majority of the patients can be managed successfully with observation and NSAIDs [26] . In situations where the MO remains painful, is restricting range of motion, causing a nerve impingement or there is a diagnostic conundrum, resection of the ossified mass is recommended [5 , 17] .…”