Solitary fibrous tumor of the pancreas

Rodríguez, Ángela de la Hoz; Martino, Marcello Di; Mazeyra, Mariel Valdivia; Martín-Pérez, Elena

doi:10.4322/acr.2021.245

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…[10] SFTs are mesenchymal tumors and have been reported to occur in various locations including the lungs, pleura, retroperitoneal space, pelvis, kidney, liver, breast, skin, pancreas, and spinal cord. [2][3][4]11] The majority of SFTs are benign; however, up to 20% of tumors are malignant. High cellularity, pleomorphism, [12] and high mitotic activity (more than 4 mitoses per 10 HPF) are the pathological criteria associated with malignancy.…”

Section: Discussionmentioning

confidence: 99%

“…Solitary fibrous tumor (SFT) is a rare soft tissue neoplasm that typically originates in the pleura, accounting for about 2% of all soft tissue neoplasms. However, SFTs can develop in a wide range of sites, [1][2][3][4] including the head and neck, lungs, liver, and pelvis. The pelvis is a little-seen site for extrathoracic SFTs, making up 6% of all SFTs.…”

Section: Introductionmentioning

confidence: 99%

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Recurrent malignant solitary fibrous tumor of pelvis: A case report and treatment approach

Zhou

2023

Medicine

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Rationale: Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that typically arise from the pleura but can also occur in various locations throughout the body. Although there are increasingly more reports of extra-pleural SFTs, reports of SFTs in bone are very rare, and a malignant SFT accompanying recurrence of pelvis has not yet been reported. Patient concerns: We herein present the case of a 15-year-old male who experienced intermittent numbness in his right buttock, accompanied by radiating pain in his lower limbs for 6 months. Radiological examinations revealed an expansive, heterogeneous enhanced mass in the sacral and iliac regions, with a branch of the right internal iliac artery feeding the tumor. Diagnoses: The histological examination suggest a diagnosis of a malignant SFT with high proliferation activity. Interventions: The sacral mass was surgically excised. Outcomes: Following the surgery, the patient experienced a local recurrence of the tumor at 9 months and was administered adjuvant imatinib treatment. Recent magnetic resonance imaging contrast-enhanced displayed shrinkage of the tumor, which may provide certain evidence for chemotherapy for the treatment of recurrence of malignant SFTs in the pelvic region. Lessons: Complete surgical excision is the recommended treatment for this rare disease entity, and the role of adjuvant therapies is controversial due to their rarity. Our case underscores the challenges in managing recurrent malignant SFTs and highlights the importance of a thorough diagnostic workup. Further research is needed to establish the role of adjuvant therapies in the management of these tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Recurrent malignant solitary fibrous tumor of pelvis: A case report and treatment approach

Zhou

2023

Medicine

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Rare hypervascular pancreatic tumors diagnosed as asynchronous metastases of central nervous system solitary fibrous tumor/hemangiopericytoma

Mizukoshi

Yamauchi

Kitaura

et al. 2021

Clin J Gastroenterol

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Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature

Wang,

Zhou,

et al. 2024

World J Clin Cases

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BACKGROUND A solitary fibrous tumor (SFT) is often located in the pleura, while SFT of the pancreas is extremely rare. Here, we report a case of SFT of the pancreas and discuss imaging, histopathology, and immunohistochemistry for accurate diagnosis and treatment. CASE SUMMARY A 54-year-old man presented to our hospital with pancreatic occupancy for over a month. There were no previous complaints of discomfort. His blood pressure was normal. Blood glucose, tumor markers, and enhanced computed tomography (CT) suggested a malignant tumor. Because the CT appearance of pancreatic cancer varies, we could not confirm the diagnosis; therefore, we performed endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB). Pathology and immunohistochemistry were consistent with SFT of the pancreas. The postoperative pathology and immunohistochemistry were consistent with the puncture results. The patient presented for a follow-up examination one month after discharge with no adverse effects. CONCLUSION Other diseases must be excluded in patients with a pancreatic mass that cannot be diagnosed. CT and pathological histology have diagnostic value for pancreatic tumors. Endoscopic puncture biopsy under ultrasound can help diagnose pancreatic masses that cannot be diagnosed preoperatively. Surgery is an effective treatment for SFT of the pancreas; however, long-term follow-up is strongly recommended because of the possibility of malignant transformation of the tumor.

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Solitary fibrous tumor of the pancreas

Cited by 4 publications

References 4 publications

Recurrent malignant solitary fibrous tumor of pelvis: A case report and treatment approach

Recurrent malignant solitary fibrous tumor of pelvis: A case report and treatment approach

Rare hypervascular pancreatic tumors diagnosed as asynchronous metastases of central nervous system solitary fibrous tumor/hemangiopericytoma

Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature

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