Full recovery of a stage IV cancer patient facing COVID-19 pandemic

Abstract

Coronavirus disease 2019 (COVID-19), first recognized in Wuhan, China, was recently declared a global pandemic by the World Health Organization (WHO). Advanced age and comorbid disease, well-known characteristics in the solid tumor population, have been reported as risk factors for severe disease and death. Cancer-related immunosuppression and its treatments also seem to play an active role in the prognosis, response, and clinical outcomes of these patients. The most effective combination therapy for COVID-19 is still under investigation, and the use of corticosteroids is controversial. Although, as a group, metastatic cancer patients are often considered not to be good candidates for ICU treatment, the individual prognosis should always come into consideration, even in a context of high pressure on medical facilities. We report the case of a stage IV prostate cancer patient infected with SARS-CoV-2 who required ICU admission and recovered from COVID-19 infection. Further studies are needed in order to identify accurate clinical prognostic criteria and provide the best treatment for these challenging patients.

Perfil de morbimortalidade de pacientes infectados pela COVID-19, evoluções e suas complicações: uma revisão integrativa

“…São classificados pacientes críticos os que apresentarem Insuficiência Respiratória Aguda (IRA) hipoxêmica ou hipercápnica, produzindo em alguns casos hipoxemia grave refratária à oxigenoterapia o que, consequentemente, reduz a SapO2, apresentando necessidade de oxigenação acima de 2 L/min para saturações acima de 94%, provoca taquipneia com frequência respiratória acima de 30 irpm e rebaixamento de consciência em casos avançados. Assim, requerem atendimento em uma UTI por possuírem alto risco de necessitar de Suporte Ventilatório Invasivo (SVI), e dessa forma se tornam expostos a agravos relacionados a disfunções hemodinâmicas devido ao uso de Drogas Vasoativas (DVA), podendo evoluir para disfunções renais e necessitarem de procedimentos invasivos de diálise (Brasil et al, 2021;Parmanande et al, 2020).…”