Using the same CIDR up to three times for estrus synchronization and artificial insemination in dairy goats

Abstract

ABSTRACT. The objective of this study was to evaluate the effectiveness of reusing a controlled internal drug release (CIDR) device for up to three times in the reproductive performance of dairy goats raised in the semi-arid zone of northeastern Brazil. Forty-five goats were allocated into three hormone treatments, as follows: CIDR1x, treated with new CIDR during nine days. Two days prior to device removal, injections of 75 g d-cloprostenol and 300 IU equine chorionic gonadotropin (eCG) were administrated. For the other treatments, the same hormone protocol was used, differing only by the use of the same CIDR for a second time in CIDR2x and for a third time in CIDR3x. The interval from device removal to the onset of estrus (13.3  1.1h vs. 13.8  2.6h vs. 13.3  1.4h), as well as estrus duration (33.6  7.3h vs. 29.6  3.2h vs. 32.8  4.5h), did not differ (p > 0.05) among groups CIDR1x, CIDR2x and CIDR3x, respectively. All synchronized females were found to be in estrus. The overall fertility and prolificacy after artificial insemination were 82.2% and 1.9 kids, respectively, without significant difference (p > 0.05) among treatments. The use of the same CIDR for up to three times was effective using 9-day estrus synchronization protocols in dairy goats. RESUMO. Uso do mesmo CIDR por até três vezes para sincronização do estro e inseminação artificial de cabras leiteiras. Objetivou-se avaliar o efeito da utilização do mesmo dispositivo de liberação controlada de drogas (CIDR) por até três vezes sobre o desempenho reprodutivo de cabras leiterias exploradas no semiárido do Nordeste Brasileiro. Foram utilizadas 45 cabras divididas em três tratamentos de sincronização do estro, sendo: CIDR1x, tratadas com CIDR novo durante nove dias. Dois dias antes da retirada do dispositivo, foram aplicados 75 g de d-cloprostenol e 300 UI de gonadotrofina coriônica eqüina (eCG). Para os demais tratamentos, foi utilizado o mesmo protocolo hormonal, diferindo apenas pelo uso do mesmo CIDR pela segunda vez no grupo CIDR2x e uso pela terceira vez no grupo CIDR3x. O intervalo entre a retirada do dispositivo e o início do estro (13,3  1,1h vs. 13,8  2,6h vs. 13,3  1,4h), bem como, a duração do estro (33,6  7,3h vs. 29,6  3,2h vs. 32,8  4,5h) não diferiram (p > 0,05) entre os grupos CIDR1x, CIDR2x e CIDR3x, respectivamente. Todas as fêmeas sincronizadas foram identificadas em estro. As médias de fertilidade e prolificidade média após inseminação artificial foram, respectivamente, de 82,2% e 1,9 crias, não havendo diferença significativa (p > 0,05) entre os tratamentos. A utilização do mesmo CIDR por até três vezes foi viável na sincronização do estro de caprinos leiteiros.Palavras-chave: tratamento hormonal, pequenos ruminantes, região Tropical, dispositivos vaginais.

Different progestagen treatment duration on estrous synchronization during the natural breeding season in non-lactating Anatolian black goats

“…The variation observed in estrous concentration in the first 12 h period after progestagen treatment among authors could be due to differences in the rate of absorption and metabolization of each progestagen and/or differences in reproductive seasonality. Considering overall estrous response for the first 12 h period (3%), our result was lower than those of Dogan et al (2005Dogan et al ( , 2008b and Nogueira et al (2011), in which different breeds of goats under different environmental conditions were studied.…”

Estrous and ovulatory responses following cervical artificial insemination in Thai-native goats given a new or once-used controlled internal drug release with human chorionic gonadotropin

“…Reuse of progesterone intravaginal devices has been reported in beef heifers and lactating beef cows (Colazo et al 2004), ewes (Ungerfeld 2009), and goats (Oliveira et al 2001;Vilarino et al 2011) usually without decreasing fertility rate. Goats that are expressing estrous cycles in typical patterns receiving new or reuse CIDR devices showed similar estrus response and pregnancy rates with second (Oliveira et al 2001) or third uses (Nogueira et al 2011). Thus, the reuse of intravaginal devices as a cost saver is a possibility to be explored in other indigenous farm animals (Vilarino et al 2010;Reyes et al 2012).…”

“…The semen was deposited into the external os of the first cervical fold, using speculum fitted with an internal light source as previously described by Vilarino et al (2011). Conception rate was determined 28 days after insemination by transrectal ultrasonography using a 7.5 MHz transducer according to Nogueira et al (2011).…”

Efficiency of Previously used CIDR Stored for a Prolonged Period

“…The residual progesterone amount in the previously used CIDR is affected by several factors including the initial progesterone concentration 1.38 Vs 1.9 g (Rathbone et al, 2002), the method of sterilization between the cycles (Zuluaga and Williams, 2008), the duration of the insertion period 7 Vs 9 days (Long et al, 2009;Carvalho et al, 2014), the number of the reusing cycles once Vs more cycles (Vilariño et al, 2011;Carvalho et al, 2014) and/or the conditions and the duration of the storage between the cycles. Except for , all previous studies reused the CIDR without storage (Nogueira et al, 2011), after storage for 48 h (Zuluaga and Williams, 2008), 7 days (Long et al 2009) or unrecorded period (Colazo et al, 2004;Carvalho et al, 2014). To our knowledge, no previous reports investigated the efficiency of the previously used CIDR after a prolonged storage.…”