Comparison of Angiotensin Receptor Blockers and Angiotensin-Converting Enzyme Inhibitors in the Management of Arterial Stiffness and Target Organ Damage in Patients with Hypertension

Abstract

Hypertension is the main modifiable cause of cardiovascular morbidity and mortality in the adult population, and it is an independent risk factor for cardiovascular disease. 1,2 Several lines of evidence have shown that there is a close relationship between arterial stiffness and hypertension and that both contribute independently to cardiovascular events and mortality. [3][4][5] The consolidation of pulse wave velocity (PWV) measurement in the assessment of arterial stiffness led several studies to demonstrate the association of this phenotype with the risk of developing different manifestations of cardiovascular disease. 6 It is the gold standard due to the reproducibility and reliability of the method and its association with cardiovascular risk in different populations. 4