“…6 Early determination of CAN is vital to the success of therapeutic input, as it has been suggested that cardiovascular denervation may be reversible if diagnosed soon after onset, through a combination of nonpharmacological and pharmacological approaches, including lifestyle modification, intensive glycemic control, and treating underlying risk factors, such as hyperlipidemia and hypertension. 9 Dias-Filho et al 10 , conducted a Brazilian multicenter study to evaluate cardiac autonomic modulation of adolescents with a family history of diabetic parents. They selected 69 teenagers from state public schools, aged 11 to 18 years, 23 with family history of diabetes.…”