Allopurinol versus Trimetazidine for the Treatment of Angina: A Randomized Clinical Trial
Tainá Viana,
Rodrigo Morel Vieira de Melo,
Diogo Freitas Cardoso Azevedo
et al.
Abstract:Background Recently, it was demonstrated that allopurinol, a xanthine oxidase inhibitor, has cardiovascular and anti-ischaemic properties and may be a metabolic antianginal agent option.Objective: The objective of this study was to evaluate the antianginal effect of allopurinol as a third drug for patients with stable coronary artery disease (CAD). Methods This was a randomized clinical trial between 2018 and 2020 including patients with CAD who maintained angina despite initial optimization with beta-blocke… Show more
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