Diagnóstico Errôneo de Angiossarcoma Cardíaco na Era COVID-19

Amin, Arash; Taheri, Zohreh; Hesami, Mahshid; Alizahehasl, Azin; Norouzi, Zeinab; Mohammadi, Nasibeh

doi:10.36660/abc.20220501

Cited by 1 publication

(1 citation statement)

References 17 publications

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“…Interestingly, since the emergence of the COVID–19 pandemic, fatal conditions may initially be misdiagnosed as COVID–19-related complications, resulting in missed opportunities for an early diagnosis of these fatal conditions. 11 Although our patient had a bloody pericardial effusion, the initial treatment focused on viral etiology, with his history of COVID-19 infection. Multiple TTEs were unremarkable except for pericardial effusion.…”

Section: Discussionmentioning

confidence: 93%

A bleeding heart: case report and review of pericardial angiosarcoma

Madan,

Mahadevia,

Sharma

et al. 2024

Autops Case Rep

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Primary cardiac tumors are rare. The cardiac sarcomas are the most common malignant cardiac tumors. These tumors have a dismal prognosis with an overall median survival of 25 months. Clinical features include dyspnea, arrhythmias, pericardial effusions, heart failure, and sudden cardiac death. The diagnosis is often challenging. Therefore, the cardiac imaging workup plays a central role in addition to a high clinical suspicion in the setting of atypical presentations that do not respond to standard therapies. The echocardiography, computed tomography, and cardiac MRI are crucial in clinching the diagnosis. Multimodal treatment with surgery, chemotherapy, and radiotherapy has been shown to improve outcomes, as opposed to using either of these modalities alone. We describe the case of a 30-year-old gentleman with COVID-19 infection who developed recurrent hemorrhagic pericardial effusions refractory to standard treatment and was eventually diagnosed as a case of pericardial angiosarcoma after his biopsy revealed the diagnosis and staging was performed using PET–CT–FDG scan. Our case re-emphasizes the importance of considering a malignant etiology early in the course of the disease presentation, especially in recurrent hemorrhagic effusions despite an inflammatory cytologic diagnosis of fluid. It also highlights the place for cardiac CT and MRI to ascertain the location and spread and to plan the further course of treatment. If diagnosed early, the estimated survival time can be prolonged by instituting a multimodal approach.

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Section: Discussionmentioning

confidence: 93%