O Prolongamento do Intervalo QTc na Admissão está Associado ao Aumento da Mortalidade em Pacientes com SARS-COV-2 durante a Hospitalização

Barbosa, Stephany; Velandía, Oscar Mauricio Muñoz; Arboleda, Alejandra Cañas; Peña, Ángel Alberto García

doi:10.36660/abc.20220155

Arquivos Brasileiros De Cardiologia

2023

DOI: 10.36660/abc.20220155

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O Prolongamento do Intervalo QTc na Admissão está Associado ao Aumento da Mortalidade em Pacientes com SARS-COV-2 durante a Hospitalização

Stephany Barbosa¹,

Oscar Mauricio Muñoz Velandía²,

Alejandra Cañas Arboleda³

et al.

Abstract: Fundamento: O envolvimento cardiovascular associado à infecção por SARS-COV-2 está relacionado a desfechos desfavoráveis durante a internação. Portanto, a medida na admissão do intervalo QTc no eletrocardiograma de 12 derivações pode ser um marcador prognóstico. Objetivo: Identificar a relação entre o prolongamento do QTc na admissão durante a hospitalização e a mortalidade por SARS-COV-2. Método: Estudo observacional baseado em uma coorte retrospectiva de pacientes com infecção confirmada por SARS-COV-2 do

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“…13,14 In this journal, Barbosa et al presented the results of an observational study that involved a significant retrospective cohort of 1,296 patients admitted to a tertiary hospital with a diagnosis of SARS-Cov-2 infection from March 2020 to July 31, 2021. 15 Of these, 127 (9, 8%) had a prolonged QTc interval. Mortality and length of hospital stay were higher in this group compared to individuals with normal QTc.…”

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Revisitando o Intervalo QT: Um Antigo Marcador para uma Nova Doença?

Camanho¹

2023

Arquivos Brasileiros De Cardiologia

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The SARS-Cov-2 (Covid-19) infection had its first cases reported in December 2019 in China and quickly spread worldwide, being announced as a pandemic in March 2020 by the World Health Organization. Respiratory manifestations are classic; however, cardiovascular complications can occur due to an indirect cardiac involvement or a direct action of the virus in the myocardial tissue. Consequently, we can find heart failure, myocarditis, arrhythmias, and cardiogenic shock. 1

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confidence: 99%

Revisitando o Intervalo QT: Um Antigo Marcador para uma Nova Doença?

Camanho¹

2023

Arquivos Brasileiros De Cardiologia

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Pathophysiological effects of SARS-CoV-2 infection on the cardiovascular system and its clinical manifestations—a mini review

Yugar

Sedenho-Prado

Schreiber

et al. 2023

Front. Cardiovasc. Med.

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Coronavirus disease 2019 (COVID-19) is a viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 may have a mild presentation, with few symptoms, or progress to a severe condition, characterized by generalized inflammation, systemic microvascular involvement, coagulopathy, and pulmonary and cardiovascular complications. Men present with more severe symptoms than women, especially men who are older and who present with comorbidities such as hypertension, diabetes mellitus, and a history of atherosclerotic diseases. Owing to its association with endothelial dysfunction, inflammation, thrombosis, and microvascular obstruction, SARS-CoV-2 infection can cause lesions in several organs, including the myocardium and the coronary arterial bed, which can result in clinical manifestations involving the cardiovascular system. In this mini review, we summarize the effects of SARS-CoV-2 infection on the cardiovascular system in both children and adults and characterize the various clinical manifestations associated with this disease.

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O Prolongamento do Intervalo QTc na Admissão está Associado ao Aumento da Mortalidade em Pacientes com SARS-COV-2 durante a Hospitalização

Cited by 2 publications

References 26 publications

Revisitando o Intervalo QT: Um Antigo Marcador para uma Nova Doença?

Revisitando o Intervalo QT: Um Antigo Marcador para uma Nova Doença?

Pathophysiological effects of SARS-CoV-2 infection on the cardiovascular system and its clinical manifestations—a mini review

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