Ceramidas Plasmáticas na Estratificação de Risco das Doenças Cardiovasculares

Paranhos, Débora Junqueira Campos; Stach, Alline; Caixeta, Adriano; Sallum, Juliana Maria Ferraz; Yasaki, Erika; Tsutsui, Jeane Mike; Rizatti, Edgar; Rochitte, Carlos Eduardo; Ching-Jianhong,; Kovalik, Jean‐Paul; Richards, A. Mark; Chan, Mark Y; Carvalho, Leonardo Pinto de

doi:10.36660/abc.20201165

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Ceramides: a New Player In Cardiovascular Disease1

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2024

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Cited by 2 publications

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“…However, despite the multiple evidence of the positive association between ceramides and CVD, the role of specific subspecies is still equivocal in this context. For instance, the role of C24:0 ceramide remains controversial being associated both positively with endothelial dysfunction, myocardial infarction with a time-dependent pattern [ 46 ] and negatively with cardiovascular mortality [ 52 , 61 ] ( Table 1 [ [37] , [38] , [39] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] ]).…”

Section: Ceramides: a New Player In Cardiovascular Diseasementioning

confidence: 99%

Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet

Spaggiari,

Angelini,

Di Vincenzo

et al. 2024

Advances in Nutrition

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Section: Ceramides: a New Player In Cardiovascular Diseasementioning

confidence: 99%

Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet

Spaggiari,

Angelini,

Di Vincenzo

et al. 2024

Advances in Nutrition

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Ceramides As Potential New Predictors of the Severity of Acute Coronary Syndrome in Conjunction with SARS-CoV-2 Infection

Lozhkina,

Gushchina,

Basov

et al. 2024

Acta Naturae

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Acute coronary events (ACEs) associated with a SARS-CoV-2 infection can significantly differ from classic ACEs. New biomarkers, such as ceramides, may help in the diagnosis and treatment of this disease. This study included 73 ACE patients for whom the SARS-CoV-2 infection was verified. Two subgroups were formed: the favorable outcome subgroup and the fatal outcome subgroup. Plasma samples were collected from all patients at the time of admission for a metabolomic analysis. The analysis of metabolites revealed that the ceramide levels were significantly lower in the fatal outcome subgroup than in the survivor subgroup. Therefore, determining ceramide levels in patients with ACEs in conjunction with COVID-19 may help assess the prognosis of these patients and manage their risks.

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Ceramidas Plasmáticas na Estratificação de Risco das Doenças Cardiovasculares

Cited by 2 publications

References 39 publications

Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet

Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet

Ceramides As Potential New Predictors of the Severity of Acute Coronary Syndrome in Conjunction with SARS-CoV-2 Infection

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