Endocardite de Prótese Valvular Aórtica por Neisseria Elongata após Procedimento de Bentall: Quando a Imagem Multimodal é Chave para o Diagnóstico

Brandão, Mariana; Gonçalves-Teixeira, Pedro; Queiros, P Ribeiro; Ferreira, Nuno; Oliveira, Marco

doi:10.36660/abc.20200706

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…In addition to our case, two of the six previously reported cases (33.3%) were found to have septic embolic phenomenon including brain and splenic infarcts [ 4 , 6 ]. N. elongata is typically sensitive to cephalosporins and aminoglycosides and is variably susceptible to penicillin.…”

Section: Discussionsupporting

confidence: 69%

Prosthetic Valve Infective Endocarditis Secondary to Neisseria elongata

Henien¹,

Malik²,

Ahmad³

2023

Cureus

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Neisseria is a large genus of bacteria consisting of organisms colonizing mucosal tracts of many animals. Neisseria elongata is a unique member, given that it is a Gram-negative rod, unlike others which are diplococci. Unlike most Neisseria species, N. elongata is catalase-negative and Superoxol-negative. These unique characteristics of N. elongata can make it more difficult to identify. Although considered to be a commensal of the nasopharyngeal tract, this organism has increasingly been identified as a cause of significant disease in humans including endocarditis. We present a case report and literature review of N. elongata causing prosthetic valve endocarditis.

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Section: Discussionsupporting

confidence: 69%

Prosthetic Valve Infective Endocarditis Secondary to Neisseria elongata

Henien¹,

Malik²,

Ahmad³

2023

Cureus

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Alternative Nuclear Imaging Tools for Infection Imaging

et al. 2022

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Purpose of Review Cardiovascular infections are serious disease associated with high morbidity and mortality. Their diagnosis is challenging, requiring a proper management for a prompt recognition of the clinical manifestations, and a multidisciplinary approach involving cardiologists, cardiothoracic surgeons, infectious diseases specialist, imagers, and microbiologists. Imaging plays a central role in the diagnostic workout, including molecular imaging techniques. In this setting, two different strategies might be used to image infections: the first is based on the use of agents targeting the microorganism responsible for the infection. Alternatively, we can target the components of the pathophysiological changes of the inflammatory process and/or the host response to the infectious pathogen can be considered. Understanding the strength and limitations of each strategy is crucial to select the most appropriate imaging tool. Recent Findings Currently, multislice computed tomography (MSCT) and nuclear imaging (18F-fluorodeoxyglucose positron emission tomography/computed tomography, and leucocyte scintigraphy) are part of the diagnostic strategies. The main role of nuclear medicine imaging (PET/CT and SPECT/CT) is the confirmation of valve/CIED involvement and/or associated perivalvular infection and the detection of distant septic embolism. Proper patients’ preparation, imaging acquisition, and reconstruction as well as imaging reading are crucial to maximize the diagnostic information. Summary In this manuscript, we described the use of molecular imaging techniques, in particular WBC imaging, in patients with infective endocarditis, cardiovascular implantable electronic device infections, and infections of composite aortic graft, underlying the strength and limitations of such approached as compared to the other imaging modalities.

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