A Síndrome de Takotsubo Existe como uma Doença Específica?

Caramelli, Bruno

doi:10.36660/abc.20200470

Cited by 1 publication

(2 citation statements)

References 5 publications

(4 reference statements)

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“…The patient in case 2 had 67 points on the InterTAK Diagnostic Score, characterizing a low probability of developing this cardiomyopathy (Table III). Acute Coronary Syndrome (ACS) and Takotsubo Syndrome can be otherwise confused, which is why [40] demonstrated in his article the difference between these two diseases, using several diagnostic criteria, as shown in Table IV. Regarding the conduct to be adopted, patients are generally referred to imaging exams.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, those with a low probability of developing TTS are directed to coronary cineangiography and those with high probability are directed to transthoracic echocardiography [39]. Although this is already a consensus among professionals, there are doubts about the most appropriate procedure to be followed due to the existence of too many diagnostic exam options, such as electrocardiogram, myocardial necrosis markers, echocardiography, coronary angiography, and magnetic resonance [40], [41], [42].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Takotsubo Syndrome and Its Genetic Relationship: Case Report and Narrative Literature Review

Ferrari

Santos²,

Alvarenga³

et al. 2022

CLINICMED

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Introduction: Takotsubo Syndrome (TTS) is presented as a temporary loss of systolic function, it is usually associated with emotional or physical stress. However, its pathophysiology is not well defined. Thus, this article seeks the relationship between the genetic factor and the development of Takotsubo Syndrome. Methodology: The study is about a narrative review and two case reports on TTS. Results: TTS is related to the excess of catecholamines, and its genetic linkage is strongly considered due to recent studies where occasionally it has been noticed its hereditary connections, such as: increased cardiac sensitivity to catecholamines and cardiac vulnerability to adrenergic stressors, impaired regulation of norepinephrine release, syndrome fragile X, and CD36 deficiency. Discussion: There is still no conclusion of the leading factors to TTS. However, being female, being in the postmenopausal period, and exposed to stressful conditions are some of the risk factors that can develop the disease, and which are better accepted by the scientific community. Conclusions: Although TTS is a disease of low prevalence, it is increasingly present in the routine of the cardiologist. The great difficulty lies in its diagnosis as it does not present a pathognomonic symptom and it is similar to other diseases, such as ACS. This causes it to pass absent-mindedly during the emergency primary investigation. Thus, there is a need to expand studies related to this disease and to investigate its genetic association.

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Section: Discussionmentioning

confidence: 99%