Quando Tudo dá Errado

Evolução da síndrome dress relacionada à fenitoína em uma jovem

“…This patient presented 6 RegiSCAR points for DRESS, including the 3 mandatory criteria. 1,3,4,[6][7][8][9] The treatment is based on suspension of the involved drug and corticosteroid therapy. It is recommended to start prednisone at a dose of 1 to 1.5mg/Kg/day, or methylprednisolone at a dose of 30mg/Kg over 3 days in severe cases.…”

“…DRESS syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is a serious adverse reaction induced by a drug, with anticonvulsants being the most associated class of drugs [1][2][3][4][5][6][7][8][9][10] . Also known as hypersensitivity syndrome drug-induced, this entity was first described by Chaiken in 1950 in an African descent man 17 days after using phenytoin.…”

“…3,7,9 Thus, it is important to have a high clinical suspicion at the very beginning presentation, as well as to know the most associated drugs, which allows its early suspension, besides the prompt as management of expected complications. 3,[7][8][9]…”