Effects of COVID-19 on tuberculosis control: past, present, and future

Silva, Denise Rossato; Mello, Fernanda Carvalho de Queiroz; Migliori, Giovanni Battista

doi:10.36416/1806-3756/e20220102

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…(5) However, recently, the COVID-19 pandemic caused negative effects on global health and reversed advances in tuberculosis control, including on a national level. (6) Among the efforts towards the elimination of tuberculosis as a public health problem, the importance of actions aimed at linking individuals to health services for effective treatment follow-up stands out. (3) This requires unique strategies focused on the specificities of individuals affected by the disease, with a focus on therapy adherence to increase cure rates, on reducing unfavorable outcomes (e.g., loss to follow-up and death), and controlling the transmission chain.…”

Section: Introductionmentioning

confidence: 99%

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001–2022

Pavinati1,

Vinícius de Lima1,

Paiva Bernardo1

et al. 2024

J Bras Pneumol.

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Objective: To analyze the temporal trend of tuberculosis cure indicators in Brazil. Methods: An ecological time-series study using administrative data on reported cases of the disease nationwide between 2001 and 2022. We estimated cure indicators for each federative unit (FU) considering individuals with pulmonary tuberculosis, tuberculosis-HIV coinfection, and those in tuberculosis retreatment. We used regression models using joinpoint regression for trend analysis, reporting the annual percentage change and the average annual percentage change. Results: For the three groups analyzed, we observed heterogeneity in the annual percentage change in the Brazilian FUs, with a predominance of significantly decreasing trends in the cure indicator in most FUs, especially at the end of the time series. When considering national indicators, an average annual percentage change of -0.97% (95% CI: -1.23 to -0.74) was identified for the cure of people with pulmonary tuberculosis, of -1.11% (95% CI: -1.42 to -0.85) for the cure of people with tuberculosis-HIV coinfection, and of -1.44% (95% CI: -1.62 to -1.31) for the cure of people in tuberculosis retreatment. Conclusions: The decreasing trends of cure indicators in Brazil are concerning and underscore a warning to public authorities, as they point to the possible occurrence of other treatment outcomes, such as treatment discontinuity and death. This finding contradicts current public health care policies and requires urgent strategies aiming to promote follow-up with patients during tuberculosis treatment in Brazil.

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Section: Introductionmentioning

confidence: 99%