Hospital admission and mortality rates for non-COVID-19 respiratory diseases in Brazil’s public health system during the covid-19 pandemic: a nationwide observational study

Albuquerque1, Diogo de Azevedo Resende de; Melo, Marcelo Dantas Tavares de; Sousa2, Thiago Lins Fagundes de; Normando, Paulo G.; Fagundes2, Juliana Góes Martins; Araújo-Filho, José de Arimateia Batista

doi:10.36416/1806-3756/e20220093

Cited by 5 publications

(6 citation statements)

References 19 publications

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“…The authors observed a 42% reduction in hospital admissions for these conditions, and for the two most prevalent chronic respiratory diseases, bronchial asthma and COPD, the reduction in hospitalization rates was approximately 46% and 45%, respectively. The second most important finding of the study 1 refers to the fact that, although the number of hospitalizations decreased, lethality increased by 60% when compared with the same indicator in the period before the pandemic.…”

mentioning

confidence: 88%

“…Na verdade, mesmo durante a pandemia, outras doenças respiratórias não desapareceram, sendo inevitável a pergunta: o que aconteceu com essas doenças em termos da dinâmica de internações hospitalares? O artigo de Resende de Albuquerque et al (1) pretende responder a essa questão avaliando os indicadores de internações e óbitos relacionados a outras doenças respiratórias que não a COVID-19 durante os primeiros meses da pandemia no Brasil. Os autores observaram uma redução de 42% nas internações por essas condições, e, para as duas doenças respiratórias crônicas mais prevalentes, asma brônquica e DPOC, a redução nas taxas de internação foi de aproximadamente 46% e 45%, respectivamente.…”

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“…Os autores observaram uma redução de 42% nas internações por essas condições, e, para as duas doenças respiratórias crônicas mais prevalentes, asma brônquica e DPOC, a redução nas taxas de internação foi de aproximadamente 46% e 45%, respectivamente. O segundo achado mais importante do estudo (1) refere-se ao fato de que, embora o número de internações tenha diminuído, a letalidade aumentou 60% quando comparada com o mesmo indicador no período anterior à pandemia.…”

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“…Alguns fatores podem ser responsáveis pelo cenário descrito por Resende de Albuquerque et al (1) Inicialmente, podemos citar as exacerbações de doenças respiratórias crônicas, notadamente a DPOC e a asma, cujos agentes infecciosos (principalmente os vírus) são os principais causadores. A implementação do distanciamento social, do uso de máscaras e da higienização das mãos com álcool em gel incorporada ao cotidiano das pessoas pode ter reduzido a exposição desses indivíduos à COVID-19 e a outros vírus respiratórios.…”

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“…The paper by Resende de Albuquerque et al 1 intends to answer this question by evaluating the indicators of hospitalization and deaths related to respiratory diseases other than COVID-19 during the first months of the pandemic in Brazil. The authors observed a 42% reduction in hospital admissions for these conditions, and for the two most prevalent chronic respiratory diseases, bronchial asthma and COPD, the reduction in hospitalization rates was approximately 46% and 45%, respectively.…”

mentioning

confidence: 99%

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What happened to non-SARS-CoV-2 respiratory diseases during the pandemic?

Silva

2023

J Bras Pneumol.

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mentioning

confidence: 88%

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mentioning

confidence: 99%

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What happened to non-SARS-CoV-2 respiratory diseases during the pandemic?

Silva

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Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients

Wichmann,

Moreira Wichmann

2023

Sci Rep

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The COVID-19 virus caused a global pandemic leading to a swift policy response. While this response was designed to prevent the spread of the virus and support those with COVID-19, there is growing evidence regarding measurable impacts on non-COVID-19 patients. The paper uses a large dataset from administrative records of the Brazilian public health system (SUS) to estimate pandemic spillover effects in critically ill health care delivery, i.e. the additional mortality risk that COVID-19 ICU hospitalizations generate on non-COVID-19 patients receiving intensive care. The data contain the universe of ICU hospitalizations in SUS from February 26, 2020 to December 31, 2021. Spillover estimates are obtained from high-dimensional fixed effects regression models that control for a number of unobservable confounders. Our findings indicate that, on average, the pandemic increased the mortality risk of non-COVID-19 ICU patients by 1.296 percentage points, 95% CI 1.145–1.448. The spillover mortality risk is larger for non-COVID patients receiving intensive care due to diseases of the respiratory system, diseases of the skin and subcutaneous tissue, and infectious and parasitic diseases. As of July 2023, the WHO reports more than 6.9 million global deaths due to COVID-19 infection. However, our estimates of spillover effects suggest that the pandemic’s total death toll is much higher.

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Risk of SARS-CoV-2 transmission in the close contacts in a small rural area in the Veneto Region (NE-Italy): past evidence for future scenarios

Bassanello,

Geppini,

Bonsembiante

et al. 2023

Front. Public Health

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BackgroundDuring the first pandemic phase of COVID-19, an epidemiological study, named First survey, was conducted on the population of a small rural area in northern Italy. In spring 2020, the results showed how a prolonged lockdown slowed down the spread of the virus.MethodsAfter contacting positive First Survey subjects and their families, those who decided to join voluntarily underwent a blood test to assess the presence of qualitative lgG about 2 months after the previous one. This was to determine if IgG persisted in individuals who tested positive in the First Survey as well as to assess the antibody status of their close family members, to determine if they were unintentionally infected.ResultsBased on serological analysis, 35.1% of the samples contained blood IgG. In subjects who tested positive during the First Survey, 62.5% remained IgG positive more than 2 months later. Among family members who were exposed to a positive relative, 23.7% were infected. Linear regression analysis showed that the presence of an infected person within a household resulted in the infection spreading to the others, but not excessively. Induced isolation extinguished the infection regardless of the extent of the contagion (intra-family or extra-family). Micro-outbreaks of SARS-Cov-2 infection which arose in the same household from extra-familial infections played a decisive role on the statistical significance of IgG-positive subjects (p < 0.001).DiscussionThe study reveal 52.6% of the IgG-positive subjects in the Second Survey came from the First Survey and 47.4% were family members previously in contact with positive subjects. Data suggest that there have been undiagnosed patients feeding the spread of the virus since the beginning of the pandemic. In conclusion, for future pandemics, it will be necessary: i) to ensure the rapid isolation of symptomatic patients and the early identification of their close contacts, ii) to carry out the maximum number of tests in the shortest possible time, both on symptomatic and asymptomatic subjects, and iii) to implement information campaigns to make people aware of their risks, and implement clear, non-conflicting communication.

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Hospital admission and mortality rates for non-COVID-19 respiratory diseases in Brazil’s public health system during the covid-19 pandemic: a nationwide observational study

Cited by 5 publications

References 19 publications

What happened to non-SARS-CoV-2 respiratory diseases during the pandemic?

What happened to non-SARS-CoV-2 respiratory diseases during the pandemic?

Big data evidence of the impact of COVID-19 hospitalizations on mortality rates of non-COVID-19 critically ill patients

Risk of SARS-CoV-2 transmission in the close contacts in a small rural area in the Veneto Region (NE-Italy): past evidence for future scenarios

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