Tuberculosis in Brazil: one country, multiple realities

Cortez, Andreza Oliveira; Melo, Angelita Cristine de; Neves, Leonardo de Oliveira; Resende, Karina Aparecida; Camargos, Paulo Augusto Moreira

doi:10.36416/1806-3756/e20200119

Cited by 29 publications

(46 citation statements)

References 22 publications

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“…Obviously, TB exposure may have occurred in an HIV patient before therapy had become effective, and is more likely in countries with high TB incidence 9 ; Brazil had in 2020 an annual number of cases of 85,721. 10 Sexual exposure is also related to GUTB risk, if mTB is detected in semen. 11 Two main mechanisms though have been suggested: either haematogenous spread from the pulmonary focus or local infection arising from the seminal vesicles or prostate via retrograde ejaculation.…”

Section: Discussionmentioning

confidence: 99%

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Two cases of testicular tuberculosis in HIV patients with distinct clinical presentations

Farias,

Vitoriano,

Ribeiro

et al. 2023

Trop Doct

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Genito-urinary tuberculosis (TB) corresponds to the second most common cause of extrapulmonary tuberculosis EPTB worldwide. It is however rare and is often clinically indistinguishable from testicular malignancy and infarction. HIV hugely increases the risk of TB in unusual sites; we present two such cases of testicular tuberculosis. The diagnosis was based respectively on histopathological findings, acid-bacilli smear of biopsy, semen, and culture.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Two cases of testicular tuberculosis in HIV patients with distinct clinical presentations

Farias,

Vitoriano,

Ribeiro

et al. 2023

Trop Doct

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“…This interruption of health services (totally or partially) was mainly in the DOT strategy, which is the most effective resource available for controlling the TB epidemic in settings with limited resources [ 46 , 47 ]. Another critical situation is the displacement of resources traditionally used in TB to Covid-19 care, such as human resources, diagnostic technologies, spaces, or offices for medical appointments [ 48 ], which impacted TB detection.…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis forecasting and temporal trends by sex and age in a high endemic city in northeastern Brazil: where were we before the Covid-19 pandemic?

et al. 2021

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Background The aim of this study was to describe the temporal trend of tuberculosis cases according to sex and age group and evidence the level of disease before the Covid-19 pandemic in a TB high endemic city. Methods This was a time series study carried out in a city in northeast Brazil. The population was composed of cases of tuberculosis, excluding those with HIV-positive status, reported between the years 2002 and 2018. An exploratory analysis of the monthly rates of tuberculosis detection, smoothed according to sex and age group, was performed. Subsequently, the progression of the trend and prediction of the disease were also characterized according to these aspects. For the trends forecast, the seasonal autoregressive linear integrated moving average (ARIMA) model and the usual Box-Jenkins method were used to choose the most appropriate models. Results A total of 1620 cases of tuberculosis were reported, with an incidence of 49.7 cases per 100,000 inhabitants in men and 34.0 per 100,000 in women. Regarding the incidence for both sexes, there was a decreasing trend, which was similar for age. Evidence resulting from the application of the time series shows a decreasing trend in the years 2002–2018, with a trend of stability. Conclusions The study evidenced a decreasing trend in tuberculosis, even before the Covid-19 pandemic, for both sex and age; however, in a step really slow from that recommended by the World Health Organization. According to the results, the disease would have achieved a level of stability in the city next years, however it might have been aggravated by the pandemic. These findings are relevant to evidence the serious behavior and trends of TB in a high endemic scenario considering a context prior to the Covid-19 pandemic.

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“…Com o retrocesso no tratamento da tuberculose devido a epidemia de HIV e AIDS nos anos 80, a Organização Mundial da Saúde (OMS) propôs um plano emergencial para o controle da tuberculose, quando em março de 1993 declarou a tuberculose como uma emergência global (Veronesi et al, 2009). Foi imposto uma meta de redução de 50% nas taxas de incidência, prevalência e mortalidade relacionada à tuberculose até 2015 (Cortez et al, 2021).…”

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O abandono do tratamento da tuberculose no Paraná entre o período de 2010 a 2021

Filho

Breda

2023

EACAD

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A Tuberculose é uma doença infectocontagiosa, cujo agente etiológico é o Mycobacterium tuberculosis, sendo transmitida através da via aérea por partículas do transmissor, atingindo mais a população de baixa renda. A tuberculose possui medicamentos eficazes contra a doença, sendo possível interromper a transmissão da doença e alcançando a cura. Porém um dos grandes problemas para o controle da tuberculose é a falta de adesão ao tratamento, muitos pacientes que possuem o diagnóstico abandonam o tratamento ou fazem uso irregular dos medicamentos, assim impedindo o controle da doença. O presente estudo que teve como objetivo analisar os casos de abandono ao tratamento da tuberculose durante o período de 2010 a 2021 no Paraná, em se tratando especificamente dos componentes sociodemográficos como faixa etária, gênero e microrregiões e outros componentes como a realização do tratamento diretamente observado (TDO). Foi realizado estudo descritivo, através dos dados notificados pelo SINAN. O trabalho demonstrou que no Paraná a taxa de abandono é 6,8%, sendo maior no sexo masculino entre 20-39 anos e o TDO não é fator que corrobora para o não abandono, Curitiba é a microrregião com a maior taxa de abandono com 37,78%. Com isso, percebeu-se que, apesar dos avanços obtidos pelo tratamento quimioterápico, ainda se nota uma carência nos serviços de Saúde e profissionais da saúde em manter uma maior relação com o paciente para que ocorra uma maior adesão ao tratamento.

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Tuberculosis in Brazil: one country, multiple realities

Cited by 29 publications

References 22 publications

Two cases of testicular tuberculosis in HIV patients with distinct clinical presentations

Two cases of testicular tuberculosis in HIV patients with distinct clinical presentations

Tuberculosis forecasting and temporal trends by sex and age in a high endemic city in northeastern Brazil: where were we before the Covid-19 pandemic?

O abandono do tratamento da tuberculose no Paraná entre o período de 2010 a 2021

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