Inflammation and all-cause mortality in patients undergoing peritoneal dialysis

Abstract

This prospective cohort study, which included 43 patients undergoing peritoneal dialysis, demonstrates that higher plasma levels of CCL2, lower plasma levels of TNF-α, and lower levels of IL-17 in the dialysate, are associated with a greater risk of transfer to hemodialysis or mortality. These findings emphasize the importance of considering local inflammation, as indicated by cytokine levels, in the risk assessment of patients undergoing peritoneal dialysis, particularly for mortality.