Antimicrobial peptide for bacterial infection imaging: first case reported in Brazil
Solange Amorim Nogueira,
Marycel Rosa Felisa Figols de Barboza,
Rosemeire Pereira Bezerra
et al.
Abstract:Molecular imaging markers can be used to differentiate between infection and aseptic inflammation, determine the severity of infection, and monitor treatment responses. One of these markers is ubiquicidin(29-41) (UBI), a cationic peptide fragment that binds to the bacterial membrane wall and is labeled with gallium-68 (
68
Ga), a positron emitter radioisotope. The use of UBI in positron emission tomography (PET)/computed tomography (CT) for improved detection of lesions has been receivin… Show more
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