Immunological Parameters and Cortisol Levels in Children With Atopic Dermatitis

Сорокман, Т В; Sokolnyk, S.V.; BABIY, Olena R.; LOZYIK, Iruna Y.; Sokolʹnyk, S. O.; Макарова, О.В.; Копчук, Т. Г.

doi:10.31688/abmu.2018.53.2.06

Cited by 2 publications

(2 citation statements)

References 22 publications

(24 reference statements)

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“…Many researchers have investigated AD and believe that the underdevelopment of skin barrier, metabolism, and gastrointestinal function, together with the family history, conditions during pregnancy, postnatal lifestyle, and environment, were closely correlated with the occurrence of AD [ 9 – 12 ]. The symbiotic microbial ecosystem formed by the intestinal flora is directly involved in human digestion, absorption, energy supply, immune regulation, fat metabolism, and many other aspects.…”

Section: Discussionmentioning

confidence: 99%

Clinical study on prevention of atopic dermatitis by oral administration of probiotics in infants

Zhao²,

Sun³

et al. 2020

Arch Med Sci

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IntroductionThis study aimed to investigate the preventive effects of oral administration of probiotics on the incidence and severity of atopic dermatitis (AD) in infants.Material and methodsA total of 396 full-term infants were enrolled in this study. Of these, 132 newborns without a family history of AD were assigned to group A, and the other 264 newborns were randomly divided into groups B and C. Infants in groups A and B were solely breastfed, while probiotics were administered to those in group C as well as breastfeeding. The information of all subjects was recorded, and the incidence of AD was followed up. The levels of serum IgE and IL-4 were measured at the age of 3 years.ResultsThe incidence of AD in infants in group B was higher than that in group A at 3 months, 4–6 months, and 7–36 months after birth, together with increased symptom scores. For infants in group C, the incidence of AD at 4–6 months and 7–36 months after birth and the SCORAD scores at 0–3 months and 4–6 months after birth were lower than those in group B. The levels of IgE and IL-4 in group B were higher than those in groups A and C at 36 months old.ConclusionsAdding probiotics could favor the establishment of the intestinal microecological balance in the neonatal period, thereby reducing the incidence of AD, decreasing the levels of serum immune indexes and alleviating the severity of the disease.

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Section: Discussionmentioning

confidence: 99%

Clinical study on prevention of atopic dermatitis by oral administration of probiotics in infants

Zhao²,

Sun³

et al. 2020

Arch Med Sci

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“…A significant role in the development and course of rosacea belongs to an impairment of the immunological reactivity of the patient 1,3,6 . The study of cytokines' role in the regulation of pathological processes in chronic dermatoses, particularly rosacea, by determining the nature of changes in the serum content of interleukins, is relevant [11][12][13][14][15][16] . Interleukins are secretory Résultats.…”

Section: Introductionmentioning

confidence: 99%

Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea

Storozhuk¹,

Denysenko²

2018

Arch Balk Med Union

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Le niveau d'interleukine-17A et d'interleukine-18 dans le sérum des patients avec l'évolution clinique différente de la rosacée Introduction. La rosacée est une dermatose chronique commune se manifestant par les lésions cutanées des zones ouvertes (visage) et au caractère torpide du traitement, ce qui détermine la pertinence de l'étude de ses facteurs pathogénétiques et l'amélioration du traitement de cette dermatose. Le but de cette étude est de déterminer et d'analyser le contenu des cytokines pro-inflammatoires-l'interleukine-17A et l'interleukine-18-dans le sérum des patients atteints de rosacée en fonction de la nature de l'évolution clinique de la dermatose. Méthodes. L'examen des 36 patients atteints de rosacée, dont les 17 ont une forme érythémateuse-télangiectasique et les 19 sont au stade papulo-pustulaire de rosacée. Chez les 18 patients, la durée de la dermatose est moins de 6 mois et, chez les autres 18, la maladie dure plus de 6 mois. On a fait le test d'immunodosage du sérum afin de révéler la teneur en cytokines-l'interleukine-17A et l'interleukine-18 (IL-17A, IL-18).

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Immunological Parameters and Cortisol Levels in Children With Atopic Dermatitis

Cited by 2 publications

References 22 publications

Clinical study on prevention of atopic dermatitis by oral administration of probiotics in infants

Clinical study on prevention of atopic dermatitis by oral administration of probiotics in infants

Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea

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